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Helicobacter Pylori Stool Antigen Assay in Hyperemesis Gravidarum: A Risk Factor for Hyperemesis Gravidarum or Not?

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Abstract

Objective: To test the hypothesis that Helicobacter pylori (H. pylori) infection may cause hyperemesis gravidarum (HG). Materials and methods: A prospective-comparative study was performed on 107 pregnant patients from October 2002 to December 2003 in a university-based prenatal care clinic. Blood and stool samples were obtained from 52 patients diagnosed as HG and 55 matched asymptomatic pregnant women. H. pylori stool antigen (HpSA) status of the participants was evaluated using a commercially available enzyme immunoassay-based kit. Results: The overall prevalence of HpSA positivity appeared as 41.1%. Twenty-two of 52 (42.3%) HG patients and 22 of 55 (40.0%) control subjects were positive for HpSA. The difference was not significant (p>.05). Conclusion: HG seemed to be not associated with H. pylori infection, as indicated by specific stool antigen assay.

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Authors and Affiliations

  1. Department of Gastroenterology, Güven Hospital, Ankara, Turkey

    Sirin Aytac

  2. Department of Gastroenterology, Fatih University School of Medicine, Ankara, Turkey

    Cansel Türkay

  3. Department of Internal Medicine, Fatih University School of Medicine, 35 Sokak 81/5, Emek, 06490, Ankara, Turkey

    Mehmet Kanbay

Authors
  1. Sirin Aytac
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  2. Cansel Türkay
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  3. Mehmet Kanbay
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Corresponding author

Correspondence to Mehmet Kanbay.

Additional information

Helicobacter pylori stool antigen assay was performed in hyperemesis gravidarum patients and matched control subjects. No difference in antigen positivity was found between the groups.

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Aytac, S., Türkay, C. & Kanbay, M. Helicobacter Pylori Stool Antigen Assay in Hyperemesis Gravidarum: A Risk Factor for Hyperemesis Gravidarum or Not?. Dig Dis Sci 52, 2840–2843 (2007). https://doi.org/10.1007/s10620-006-9709-9

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  • DOI: https://doi.org/10.1007/s10620-006-9709-9

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