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Interaction of 5-methoxy-4-azatricyclo[4.3.1.13,8]-undec-4-ene with nitrogen-containing nucleophiles

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Chemistry of Heterocyclic Compounds Aims and scope

The interaction of 5-methoxy-4-azatricyclo[4.3.1.13,8]undec-4-ene with acid hydrazides has been studied. It has been established that its reaction with methoxycarbonylhydrazine leads to the formation of 6,7,8,9,10,11-hexahydro-5H-5,9:7,11-dimethano[1,2,4]triazolo[4,3-a]azocin-3-one. Special features of the alkylation of this substrate under various conditions have been studied.

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References

  1. N. Tsuzuki, T. Hama, M. Kawada, A. Hasui, R. Konoshi, S. Shiwa, Y. Ochi, S. Futaki, and K. Kitagawa, J. Pharm. Sci., 83, 481 (1994).

    Article  CAS  Google Scholar 

  2. N. Lomadze and H.-J. Schneider, Tetrahedron Lett., 43, 4403 (2002).

    Article  CAS  Google Scholar 

  3. V. G. Keizer and J. G. Korsloot, J. Med. Chem., 14, 411 (1971).

    Article  CAS  Google Scholar 

  4. K. V. Bolshakov, D. B. Tikhonov, V. E. Gmiro, and L. G. Magazanik, Neurosci. Lett., 291, 101 (2000).

    Article  CAS  Google Scholar 

  5. G. Zoidis, I. Papanastasiou, I. Dotsikas, A. Sandoval, R. G. Dos Santos, Z. Papadopoulou-Daifoti, A. Vamvakides, N. Kolocouris, and R. Felix, Bioorg. Med. Chem., 13, 2791 (2005).

    Article  CAS  Google Scholar 

  6. Z. Kazimierczuk, A. Gorska, T. Switaj, and W. Lasek, Bioorg. Med. Chem. Lett., 11, 1197 (2001).

    Article  CAS  Google Scholar 

  7. E. A. Knyazeva, M. Yu. Skomorokhov, and Yu. N. Klimochkin, Khim. Geterotsikl. Soedin., 1731 (2010). [Chem. Heterocycl. Compd., 46, 1407 (2010).]

    Google Scholar 

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Authors and Affiliations

  1. Samara State Technological University, 244 Molodogvardeiskaya St., Samara, 443100, Russia

    E. A. Knyazeva, M. Yu. Skomorokhov, D. V. Osipov & Yu. N. Klimochkin

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  1. E. A. Knyazeva
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  2. M. Yu. Skomorokhov
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  3. D. V. Osipov
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  4. Yu. N. Klimochkin
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Correspondence to E. A. Knyazeva.

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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 10, pp. 1629-1633, October, 2012.

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Knyazeva, E.A., Skomorokhov, M.Y., Osipov, D.V. et al. Interaction of 5-methoxy-4-azatricyclo[4.3.1.13,8]-undec-4-ene with nitrogen-containing nucleophiles. Chem Heterocycl Comp 48, 1517–1521 (2013). https://doi.org/10.1007/s10593-013-1166-8

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  • DOI: https://doi.org/10.1007/s10593-013-1166-8

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