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Synthesis and structure of a new heterocyclic system – 7,8-dihydroimidazo- [1,2-c][1,3]thiazolo[4,5-e]pyrimidine

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Chemistry of Heterocyclic Compounds Aims and scope

The purpose-directed synthesis of a new heterocyclic system, 7,8-dihydroimidazo[1,2-c][1,3]thia- zolo[4,5-e]pyrimidine has been carried out based on the successive interaction of available 2-(aroyl- aminocyanomethylene)imidazolidines with hydrogen sulfide and triethyl orthoformate with subsequent intramolecular cyclocondensation of the obtained 8-aroylamino-7-thioxo-1,2,3,7-tetrahydroimidazo- [1,2-c]pyrimidines under the action of phosphorus pentasulfide or polyphosphoric acid.

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Authors and Affiliations

  1. Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Sciences of Ukraine, 1Murmanska St., Kyiv, 02660, Ukraine

    A. P. Kozachenko, O. V. Shablykin, A. N. Vasilenko & V. S. Brovarets

  2. Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 5 Murmanska St., Kyiv, 02094, Ukraine

    A. N. Chernega

Authors
  1. A. P. Kozachenko
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  2. O. V. Shablykin
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  3. A. N. Vasilenko
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  4. A. N. Chernega
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  5. V. S. Brovarets
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Corresponding author

Correspondence to V. S. Brovarets.

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 4, pp. 613–620, April, 2011.

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Kozachenko, A.P., Shablykin, O.V., Vasilenko, A.N. et al. Synthesis and structure of a new heterocyclic system – 7,8-dihydroimidazo- [1,2-c][1,3]thiazolo[4,5-e]pyrimidine. Chem Heterocycl Comp 47, 507–513 (2011). https://doi.org/10.1007/s10593-011-0788-y

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  • DOI: https://doi.org/10.1007/s10593-011-0788-y

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