The acid hydrolysis of a series of 5-aryl-3-(β-thiomorpholinoethyl)-1,2,4-oxadiazoles gave substituted benzoic acids and 2-amino-8-thia-1-aza-5-azoniaspiro[4.5]dec-1-ene chloride hydrate, whose structure was demonstrated by spectral methods and X-ray diffraction structural analysis.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, Vol. 46, No. 7, pp. 1086-1096, July, 2010.
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Kayukova, L.A., Orazbaeva, M.A., Gapparova, G.I. et al. Rapid acid hydrolysis of 5-aryl-3-(β-thiomorpholinoethyl)-1,2,4-oxadiazoles. Chem Heterocycl Comp 46, 879–886 (2010). https://doi.org/10.1007/s10593-010-0597-8
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DOI: https://doi.org/10.1007/s10593-010-0597-8