The synthesis of 3-substituted 4(3H)-quinazolinones from anthranilic acid, orthoesters, and amines in the presence of ceric ammonium nitrate has been studied. The reaction occurred in a few minutes at room temperature under solvent-free conditions and in excellent yields. The probable conversion mechanism has been discussed.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 733–736, April, 2010.
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Wang, M., Song, Z.G. & Zhang, T.T. Synthesis of 3-substituted 4(3h)-quinazolinones catalyzed by ceric ammonium nitrate. Chem Heterocycl Comp 46, 581–584 (2010). https://doi.org/10.1007/s10593-010-0548-4
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DOI: https://doi.org/10.1007/s10593-010-0548-4