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A Solvent-Free Process for Synthesis of Imines by Iron-Catalyzed Oxidative Self- or Cross-Condensation of Primary Amines Using Molecular Oxygen as Sole Oxidant

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Abstract

The synthesis of imines by oxidative self- or cross-condensation of primary amines has been achieved using iron(II) bromide as the catalyst. The protocol is ligand-free, additive-free, solvent-free, and high-yielding and utilizes renewable oxygen as sole oxidant. The reaction tolerated a wide range of functionalities.

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Acknowledgments

This work was supported by the University of Delhi through R & D Grant and DU/DST-Purse Grant for promoting the Basic Research in the University. A.S. give thanks the University Grants Commission for fellowship.

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Authors and Affiliations

  1. Organic Synthesis and Catalysis Laboratory, Department of Chemistry, University of Delhi, Delhi, 110007, India

    Kovuru Gopalaiah & Anupama Saini

Authors
  1. Kovuru Gopalaiah
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  2. Anupama Saini
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Corresponding author

Correspondence to Kovuru Gopalaiah.

Additional information

Dedicated to Professor Pavan Mathur on the occasion of his 65th birthday.

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Gopalaiah, K., Saini, A. A Solvent-Free Process for Synthesis of Imines by Iron-Catalyzed Oxidative Self- or Cross-Condensation of Primary Amines Using Molecular Oxygen as Sole Oxidant. Catal Lett 146, 1648–1654 (2016). https://doi.org/10.1007/s10562-016-1789-3

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  • DOI: https://doi.org/10.1007/s10562-016-1789-3

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