Abstract
Coronary artery vasculitis is rare and comprises an array of inflammatory diseases. It often results in severe and life-threatening complications, including coronary artery aneurysm, coronary artery stenosis, intraluminal thrombosis, and microcirculation abnormalities. These may occur at a young age and are often silent in the early phases. Invasive coronary angiography is the gold standard for diagnosing coronary artery disease (CAD); however, multi-detector computed tomography (MDCT) is now widely regarded as a powerful non-invasive tool for the detection of CAD. It is important for clinicians to recognize the various CT findings associated with coronary artery vasculitis in order to promote accurate diagnosis and proper patient management. The purpose of this article is to present an overview of the conditions associated with coronary artery vasculitis, with an emphasis on etiology and cardiac MDCT diagnosis of CAD. Cardiac MDCT is clinically useful and can provide information for the accurate diagnosis and treatment of coronary vasculitis.
Similar content being viewed by others
References
Eleftheriadis D, Eleftheriadis N (2012) Coronary artery disease and systemic vasculitis: case report and review. In: Chaikovsky I (ed) Coronary artery diseases. InTech, Zagreb, pp 281–301
Amezcua-Guerra LM, Pineda C (2007) Imaging studies in the diagnosis and management of vasculitis. Curr Rheumatol Rep 9:320–327
Hansson GK (2005) Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 352:1685–1695
Park JH, Chung JW, Im JG et al (1995) Takayasu arteritis: evaluation of mural changes in the aorta and pulmonary artery with CT angiography. Radiology 196:89–93
Lupi-Herrera E, Sánchez-Torres G, Marcushamer J et al (1977) Takayasu’s arteritis. Clinical study of 107 cases. Am Heart J 93:94–103
Amano J, Suzuki A (1991) Coronary artery involvement in Takayasu’s arteritis. Collective review and guideline for surgical treatment. J Thorac Cardiovasc Surg 102:554–560
Endo M, Tomizawa Y, Nishida H et al (2003) Angiographic findings and surgical treatments of coronary artery involvement in Takayasu arteritis. J Thorac Cardiovasc Surg 125:570–577
Kang E-J, Kim SM, Choe YH et al (2014) Takayasu arteritis: assessment of coronary arterial abnormalities with 128-section dual-source CT angiography of the coronary arteries and aorta. Radiology 270:74–81
Hata A, Onouchi Y (2009) Susceptibility genes for Kawasaki disease: toward implementation of personalized medicine. J Hum Genet 54:67–73
Wood LE, Tulloh R (2009) Kawasaki disease in children. Heart 95:787–792
Steeds R, Mohiaddin R (2006) Takayasu arteritis: role of cardiovascular magnetic imaging. Int J Cardiol 109:1–6
Fukushige J, Nihill MR, McNamara DG (1980) Spectrum of cardiovascular lesions in mucocutaneous lymph node syndrome: analysis of eight cases. Am J Cardiol 45:98–107
Tsuda E, Abe T, Tamaki W (2010) Acute coronary syndrome in adult patients with coronary artery lesions caused by Kawasaki disease: review of case reports. Cardiol Young 21:74
Cho YK, Lee W, Choi SI et al (2008) Cardiovascular Behçet disease: the variable findings of rare complications with CT angiography and conventional angiography and its interventional management. J Comput Assist Tomogr 32:679–689
Koq Y, Gfillfi I, Akpek G (1992) Vascular involvement in Behçet’s Disease. J Rheumatol 19:402–410
Arishiro K, Nariyama J, Hoshiga M et al (2006) Vascular Behcet’s disease with coronary artery aneurysm. Intern Med 45:903–907
Sismanoglu M, Omeroglu SN, Mansuroglu D et al (2005) Coronary artery disease and coronary artery bypass grafting in Behçet’s disease. J Card Surg 20:160–163
Stone JH, Zen Y, Deshpande V (2012) IgG4-related disease. N Engl J Med 366(6):539–551
Ishizaka N (2013) IgG4-related disease underlying the pathogenesis of coronary artery disease. Clin Chim Acta 415:220–225
Matsumoto Y, Kasashima S, Kawashima A et al (2008) A case of multiple immunoglobulin G4-related periarteritis: a tumorous lesion of the coronary artery and abdominal aortic aneurysm. Hum Pathol 39:975–980
Maturen KE, Sundaram B, Marder W et al (2012) Coronary artery involvement in idiopathic retroperitoneal fibrosis: computed tomographic findings. J Thorac Imaging 27:W35
Noth I, Strek ME, Leff AR (2003) Churg–Strauss syndrome. Lancet 361:587–594
Keogh KA, Specks U (2003) Churg–Strauss syndrome: clinical presentation, antineutrophil cytoplasmic antibodies, and leukotriene receptor antagonists. Am J Med 115:284
Hellemans S, Dens J, Knockaert D (1997) Coronary involvement in the Churg–Strauss syndrome. Heart 77:576–578
Guillevin L, Cohen P, Gayraud M et al (1999) Churg–Strauss syndrome clinical study and long-term follow-up of 96 patients. Medicine 78:26
Sablé-Fourtassou R, Cohen P, Mahr A et al (2005) Antineutrophil cytoplasmic antibodies and the Churg–Strauss syndrome. Ann Intern Med 143:632
Scott RM, Smith ER (2009) Moyamoya disease and moyamoya syndrome. N Engl J Med 360:1226–1237
Halley S, White W, Ramsby G et al (1988) Renovascular hypertension in moyamoya syndrome. Therapeutic response to percutaneous transluminal angioplasty. Am J Hypertens 1:348–352
Togao O, Mihara F, Yoshiura T et al (2004) Prevalence of stenoocclusive lesions in the renal and abdominal arteries in moyamoya disease. Am J Roentgenol 183:119–122
Akasaki T, Kagiyama S, Omae T et al (1998) Asymptomatic moyamoya disease associated with coronary and renal artery stenoses—a case report. Jpn Circ J 62:136
Tokunaga Y, Toyoda K, Ago T et al (1996) Systemic vascular change associated with moyamoya-like cerebrovascular disease and microvascular coronary artery disease. Clin Neurol 36:318–322
Komiyama M, Nishikawa M, Yasui T et al (2001) Moyamoya disease and coronary artery disease. Case report. Neurol Med Chir 41:37–41
St. Goar FG, Gominak SC, Potkin BN (1999) Bilateral aortoostial coronary artery disease: moyamoya of the heart? Am J Cardiol 83:1296
Kono S, Oka K, Sueishi K (1990) Histopathologic and morphometric studies of leptomeningeal vessels in moyamoya disease. Stroke 21:1044–1050
Acknowledgments
This work was supported by the National Research Foundation of Korea (NRF) grant funded by the Korea government (MEST) (No. 2011-0023624).
Conflict of interest
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Jeon, C.H., Kim, Y.K., Chun, E.J. et al. Coronary artery vasculitis: assessment with cardiac multi-detector computed tomography. Int J Cardiovasc Imaging 31 (Suppl 1), 59–67 (2015). https://doi.org/10.1007/s10554-015-0652-8
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10554-015-0652-8