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Assessment of right ventricular volumes and function using cardiovascular magnetic resonance cine imaging after atrial redirection surgery for complete transposition of the great arteries

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Abstract

Cardiovascular magnetic resonance (CMR) imaging is the reference standard for measurement of right ventricular (RV) volumes and function. To date, no study has compared methods of data acquisition and analysis by CMR for adults with a systemic RV. Our objective was to evaluate RV size and function using axial and short axis views in adults post atrial switch (Mustard) surgery. A total of 34 adults (20 male, mean age at CMR 32 ± 6 years) were identified at our centre. Volumes, RV end-diastolic (EDV) and end-systolic (ESV) were measured in short axis and axial orientations by two independent experienced readers, blinded to clinical and CMR data. Intra and interobserver measurements in each view were compared using Bland–Altman plots and intraclass correlation coefficients (ICC). Although mean volumes were larger in the axial as compared with the short axis view [RVEDV 247 ± 67 vs. 233 ± 54 ml (p = 0.002) and RVESV 148 ± 54 vs. 136 ± 50 ml (p = 0.001)], mean RV ejection fractions (EF) were similar [41 ± 9 % vs. 43 ± 12 % (p = 0.13)]. Bland–Altman plots demonstrated better agreement for axial measures of RVEDV and right ventricular ejection fraction (RVEF) within and between observers. Similarly, ICC values were stronger for axial as compared with short axis volumes and function—intraobserver RVEDV 0.99 (0.98–0.99) versus 0.96 (0.92–0.98) and RVEF 0.96 (0.93–0.98) versus 0.90 (0.82–0.95); interobserver RVEDV 0.97 (0.94–0.98) versus 0.90 (0.73–0.95) and RVEF 0.85 (0.53–0.94) versus 0.82 (0.67–0.90). Axially derived measurements of RV volumes and function have better agreement and reproducibility as compared with short axis values; whereas axial volumes tend to be larger, RVEF is not significantly different between the two methods.

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Authors and Affiliations

  1. Department of Medical Imaging, Toronto General Hospital, University Health Network, University of Toronto, 200 Elizabeth St, Toronto, ON, M5G 2C4, Canada

    Laura Jimenez-Juan, Bernd J. Wintersperger, Sebastian Ley, Andrew M. Crean, Elsie T. Nguyen, Djeven P. Deva & Narinder S. Paul

  2. Division of Cardiology, St Michael’s Hospital, University of Toronto, 30 Bond St, Toronto, ON, M5B 1W8, Canada

    Subodh B. Joshi & Andrew T. Yan

  3. Division of Cardiology, Toronto Congenital Cardiac Centre for Adults, Peter Munk Cardiac Centre, Toronto General Hospital, University Health Network, University of Toronto, 200 Elizabeth St, Toronto, ON, M5G 2C4, Canada

    Andrew M. Crean & Rachel M. Wald

  4. Division of Cardiology, Labatt Family Heart Centre, Hospital for Sick Children, University of Toronto, 555 University Avenue, Toronto, ON, M5G 1X8, Canada

    Rachel M. Wald

  5. Department of Clinical Radiology, University Hospitals Munich, Ludwig-Maximilians-University Munich, 15 Marchioninistr, 81377, Munich, Germany

    Bernd J. Wintersperger

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  1. Laura Jimenez-Juan
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  2. Subodh B. Joshi
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  3. Bernd J. Wintersperger
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  4. Andrew T. Yan
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  5. Sebastian Ley
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  7. Elsie T. Nguyen
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  10. Rachel M. Wald
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Correspondence to Rachel M. Wald.

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Jimenez-Juan, L., Joshi, S.B., Wintersperger, B.J. et al. Assessment of right ventricular volumes and function using cardiovascular magnetic resonance cine imaging after atrial redirection surgery for complete transposition of the great arteries. Int J Cardiovasc Imaging 29, 335–342 (2013). https://doi.org/10.1007/s10554-012-0083-8

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  • DOI: https://doi.org/10.1007/s10554-012-0083-8

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