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Dietary patterns and endometrial cancer risk in the California Teachers Study cohort

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Abstract

Purpose

Information on the role of dietary patterns and endometrial cancer risk is limited. We investigated whether dietary patterns are associated with endometrial cancer risk among women in the California Teachers Study cohort.

Methods

Among 75,093 eligible women, 937 developed invasive endometrial cancer between 1995 and 2011. Multivariate Cox regression was performed to estimate relative risks (RR) and 95 % confidence intervals (CI) associated with five dietary patterns identified by principal components factor analysis: “plant-based,” “high protein/high fat,” “high carbohydrates,” “ethnic,” and “salad and wine.”

Results

These dietary patterns were not associated with endometrial cancer risk overall (RR = 0.91, 95 % CI: 0.72, 1.15 for the highest vs. lowest quintile of the “plant-based” dietary pattern) or by menopausal status and hormone therapy use.

Conclusions

Dietary patterns do not seem to be associated with endometrial cancer risk.

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Acknowledgments

This work was supported by grant R01 CA77398 from the National Cancer Institute. The collection of cancer incidence data used in this study was supported by the California Department of Public Health (CDPH) as part of the statewide cancer reporting program mandated by California Health and Safety Code Section 103885; the NCI’s SEER program under contract HHSN261201000140C awarded to the Cancer Prevention Institute of California, contract HHSN261201000035C awarded to the University of Southern California, and contract HHSN261201000034C awarded to the Public Health Institute; and the Centers for Disease Control and Prevention’s (CDCP) National Program of Cancer Registries, under agreement U58DP003862-01 awarded to the CDPH. The ideas and opinions expressed herein are those of the author(s), and endorsement by the CDPH, NCI, and CDCP or their contractors and subcontractors is not intended nor should be inferred.

Conflict of interest

The authors declare that they have no conflict of interest.

Author information

Authors and Affiliations

  1. Cancer Prevention Institute of California, 2201 Walnut Avenue, Suite 300, Fremont, CA, 94538, USA

    Alison J. Canchola & Pamela L. Horn-Ross

  2. Beckman Research Institute, City of Hope, Duarte, CA, USA

    James V. Lacey Jr. & Leslie Bernstein

Authors
  1. Alison J. Canchola
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  2. James V. Lacey Jr.
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  3. Leslie Bernstein
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  4. Pamela L. Horn-Ross
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Corresponding author

Correspondence to Alison J. Canchola.

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Canchola, A.J., Lacey, J.V., Bernstein, L. et al. Dietary patterns and endometrial cancer risk in the California Teachers Study cohort. Cancer Causes Control 26, 627–634 (2015). https://doi.org/10.1007/s10552-015-0552-1

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  • DOI: https://doi.org/10.1007/s10552-015-0552-1

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