Abstract
We demonstrated specific features of oxidative damage to mitochondrial translation products in animals were revealed after fractionated X-ray exposure in low doses. Differences were found in carbonylation and oxidation of SH groups in irradiated rats and irradiated tumor-bearing animals. Our results indicate that preliminary fractionated X-ray exposure determines oxidative damage to these mitochondrial proteins only at the initial stage of the study, while in the follow-up period major role is played the by tumor development.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 144, No. 10, pp. 401–403, October, 2007
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Marchenko, M.M., Kopyl’chuk, G.P. & Voloshchuk, O.M. Oxidative destruction of mitochondrial translation products after fractionated irradiation of rats with tumor. Bull Exp Biol Med 144, 520–522 (2007). https://doi.org/10.1007/s10517-007-0366-6
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DOI: https://doi.org/10.1007/s10517-007-0366-6