Applied Psychophysiology and Biofeedback

, Volume 35, Issue 4, pp 293–302

Neurofeedback Intervention in Fibromyalgia Syndrome; a Randomized, Controlled, Rater Blind Clinical Trial

Authors

  • Sadi Kayıran
    • Department of Physical Medicine and RehabilitationFaculty of Medicine, Kocaeli University
    • Department of Physical Medicine and RehabilitationFaculty of Medicine, Kocaeli University
  • Nigar Dursun
    • Department of Physical Medicine and RehabilitationFaculty of Medicine, Kocaeli University
  • Numan Ermutlu
    • Department of PhysiologyFaculty of Medicine, Istanbul Science University
  • Sacit Karamürsel
    • Department of PhysiologyIstanbul Faculty of Medicine, Istanbul University
Article

DOI: 10.1007/s10484-010-9135-9

Cite this article as:
Kayıran, S., Dursun, E., Dursun, N. et al. Appl Psychophysiol Biofeedback (2010) 35: 293. doi:10.1007/s10484-010-9135-9

Abstract

We designed a randomized, rater blind study to assess the efficacy of EEG Biofeedback (Neurofeedback-NFB) in patients with fibromyalgia syndrome (FMS). Eighteen patients received twenty sessions of NFB-sensory motor rhythm (SMR) treatment (NFB group) during 4 weeks, and eighteen patients were given 10 mg per day escitalopram treatment (control group) for 8 weeks. Visual Analog Scales for pain and fatigue, Hamilton and Beck Depression and Anxiety Inventory Scales, Fibromyalgia Impact Questionnaire and Short Form 36 were used as outcome measures which were applied at baseline and 2nd, 4th, 8th, 16th, 24th weeks. Mean amplitudes of EEG rhythms (delta, theta, alpha, SMR, beta1 and beta2) and theta/SMR ratio were also measured in NFB group. All post-treatment measurements showed significant improvements in both of the groups (for all parameters p < 0.05). NFB group displayed greater benefits than controls (for all parameters p < 0.05). Therapeutic efficacy of NFB was found to begin at 2nd week and reached to a maximum effect at 4th week. On the other hand, the improvements in SSRI treatment were also detected to begin at 2nd week but reached to a maximum effect at 8th week. No statistically significant changes were noted regarding mean amplitudes of EEG rhythms (p > 0.05 for all). However, theta/SMR ratio showed a significant decrease at 4th week compared to baseline in the NFB group (p < 0.05). These data support the efficacy of NFB as a treatment for pain, psychological symptoms and impaired quality of life associated with fibromyalgia.

Keywords

Fibromyalgia syndrome Neurofeedback Escitalopram

Copyright information

© Springer Science+Business Media, LLC 2010