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Non-invasive imaging of angiogenesis in head and neck squamous cell carcinoma

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Abstract

Squamous cell carcinoma of the head and neck (HNSCC) is the seventh most common cancer in the United States. Angiogenesis, the process by which new blood vessels are formed, is an essential element at the basis of both tumor growth and metastases. This review discusses pertinent aspects of the role of imaging modalities in assessing angiogenesis and anti-angiogenic therapy in advanced HNSCC.

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Acknowledgments

We thank Ms. Ada Muellner (B.A.) for editing the manuscript and Dr Diane Carlson (Dept of Pathology) for molecular pathology data on surgical specimens. The work from MSKCC reported in this review was supported by the National Cancer Institute/National Institutes of Health (grant number 1 R01 CA115895).

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  1. Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA

    Jacobus F. A. Jansen, Jason A. Koutcher & Amita Shukla-Dave

  2. Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY, USA

    Jacobus F. A. Jansen, Jason A. Koutcher & Amita Shukla-Dave

  3. Department of Medicine, Memorial Sloan-Kettering Cancer Center, New York, NY, USA

    Jason A. Koutcher

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Correspondence to Amita Shukla-Dave.

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Jansen, J.F.A., Koutcher, J.A. & Shukla-Dave, A. Non-invasive imaging of angiogenesis in head and neck squamous cell carcinoma. Angiogenesis 13, 149–160 (2010). https://doi.org/10.1007/s10456-010-9167-z

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