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Coupled Simulation of Heart Valves: Applications to Clinical Practice

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Abstract

The last few decades have seen great advances in the understanding of heart valves, and consequently, in the development of novel treatment modalities and surgical procedures for valves afflicted by disease. This is due in part to the profound advancements in computing technology and noninvasive medical imaging techniques that have made it possible to numerically model the complex heart valve systems characterized by distinct features at different length scales and various interacting processes. In this article, we highlight the importance of explicitly coupling these multiple scales and diverse processes to accurately simulate the true behavior of the heart valves, in health and disease. We examine some of the computational modeling studies that have a direct consequence on clinical practice.

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Conflict of interest

This statement is to declare that we, Ahmed Bakhaty and Mohammad Mofrad, the authors of article “Coupled Simulation of the Heart Valve: Applications to Clinical Practice” do not possess any financial relationships that might bias our work. We hereby declare that no conflict of interest exists in our work.

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  1. Departments of Bioengineering and Mechanical Engineering, University of California, 208A Stanley Hall #1762, Berkeley, CA, 94720-1762, USA

    Ahmed A. Bakhaty & Mohammad R. K. Mofrad

  2. Department of Civil and Environmental Engineering, University of California, Berkeley, CA, USA

    Ahmed A. Bakhaty

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  1. Ahmed A. Bakhaty
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Correspondence to Mohammad R. K. Mofrad.

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Associate Editor Estefanía Peña oversaw the review of this article.

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Bakhaty, A.A., Mofrad, M.R.K. Coupled Simulation of Heart Valves: Applications to Clinical Practice. Ann Biomed Eng 43, 1626–1639 (2015). https://doi.org/10.1007/s10439-015-1348-x

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