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Centrifuge-based deterministic lateral displacement separation

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Abstract

This work investigates the migration of spherical particles of different sizes in a centrifuge-driven deterministic lateral displacement device. Specifically, we use a scaled-up model to study the motion of suspended particles through a square array of cylindrical posts under the action of centrifugation. Experiments show that separation of particles by size is possible depending on the orientation of the driving acceleration with respect to the array of posts (forcing angle). We focus on the fractionation of binary suspensions and measure the separation resolution at the outlet of the device for different forcing angles. We found excellent resolution at intermediate forcing angles, when large particles are locked to move at small migration angles, but smaller particles follow the forcing angle more closely. Finally, we show that reducing the initial concentration (number) of particles, approaching the dilute limit of single particles, leads to increased resolution in the separation.

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Acknowledgments

This work was partially supported by the National Science Foundation Grant No. CBET-1339087, along with support from the Rutgers School of Engineering, the Department of Mechanical and Aerospace Engineering and an A. Walter Tyson Assistant Professorship Award. We also thank Maxim Lazoutchenkov, Brett Cecere, Maxwell Berka, Derek Dechent, Kshitij Minhas, Mark Mettias and Joseph Stephens for working on the design of the device as part of their senior design course. Finally, we acknowledge Saugata Dutt, Sandesh Gopinath and Chen Yang for their assistance with the experimental setup.

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Authors and Affiliations

  1. Department of Mechanical and Aerospace Engineering, Rutgers, The State University of New Jersey, Piscataway, NJ, 08854, USA

    Mingliang Jiang, Aaron D. Mazzeo & German Drazer

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  1. Mingliang Jiang
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  2. Aaron D. Mazzeo
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  3. German Drazer
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Correspondence to German Drazer.

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Jiang, M., Mazzeo, A.D. & Drazer, G. Centrifuge-based deterministic lateral displacement separation. Microfluid Nanofluid 20, 17 (2016). https://doi.org/10.1007/s10404-015-1686-x

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