Abstract
Objective
The authors investigated the effectiveness of a functionalized tricalcium phosphate (fTCP) combined with a low fluoride level in a mouthrinse to reharden eroded enamel lesions.
Methods
Ninety enamel slabs attached in pairs to removable appliances were randomly assigned to three treatment groups (n = 30/group): (T1) NaF rinse (225 ppm F + 40 ppm fTCP), (T2) NaF rinse (225 ppm F; ACT®), and (T3) no mouthrinse (saliva). While wearing the in situ appliance for 14 days, subjects brushed their teeth with 1100 ppm F toothpaste (Crest©) for 2 min, rinsed with 15 ml of water for 10s, and then rinsed with 15 ml of their assigned treatment mouthrinse. Treatment efficacy was evaluated using surface microhardness (SMH) and transverse microradiography (TMR). Intra- and intergroup comparisons (α = 0.05) were performed using the t-test and ANOVA followed by the Tukey test (HSD).
Results
With SMH, intragroup comparison (t-test) indicated significant rehardening of the eroded lesion with exposure to T1 (p < 0.001) and T2 (p < 0.01) but not with T3 However, with TMR, remineralization was only significant (p = 0.01) with T1, but not with T2 and T3. In the intergroup comparison with percentage change in SMH, T1 was significantly different from T3 (p < 0.01; Tukey HSD) but not from T2, and T2 was significantly different from T3. Intergroup comparison based on percentage mineral gain showed that T2 (p = 0.02) and T3 (p = 0.01) differed significantly from fTCP, but not between each other.
Conclusion
Addition of low level fluoride to functionalized β-tricalcium phosphate promoted rehardening of eroded enamel lesions.
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The present study had its own financing. The authors would like to thank the Coordination of Training of Higher Education Graduates (CAPES) for the scholarship (BEX# 6636-10).
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The authors declare no conflict of interest in this work with a personal or financial relationship that might have introduced any bias or affected our judgment.
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The Local Institutional Ethics Committee granted ethical approval for the study. The study followed the guidelines of Good Clinical Practice and was conducted in full accordance with the ethical standards of the Institutional Research Committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. All participants signed the informed written consent.
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de Oliveira, A.F.B., Mathews, S.M., Ramalingam, K. et al. The effectiveness of an NaF rinse containing fTCP on eroded enamel remineralization. J Public Health 24, 147–152 (2016). https://doi.org/10.1007/s10389-016-0709-8
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DOI: https://doi.org/10.1007/s10389-016-0709-8