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Mother-induced hypertension in familial dysautonomia

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Abstract

Here we report the case of a patient with familial dysautonomia (a genetic form of afferent baroreflex failure), who had severe hypertension (230/149 mmHg) induced by the stress of his mother taking his blood pressure. His hypertension subsided when he learnt to measure his blood pressure without his mother’s involvement. The case highlights how the reaction to maternal stress becomes amplified when catecholamine release is no longer under baroreflex control.

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Acknowledgments

This work was funded by the Dysautonomia Foundation, the Food and Drug Administration’s Office of Orphan Product Development (R01FD004772), and the National Institutes of Office of Rare Disease Research (U54 NS065736).

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Authors and Affiliations

  1. Dysautonomia Center, Department of Neurology, New York University, New York, NY, 10016, USA

    Lucy Norcliffe-Kaufmann, Jose-Alberto Palma & Horacio Kaufmann

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  1. Lucy Norcliffe-Kaufmann
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  2. Jose-Alberto Palma
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  3. Horacio Kaufmann
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Correspondence to Lucy Norcliffe-Kaufmann.

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Norcliffe-Kaufmann, L., Palma, JA. & Kaufmann, H. Mother-induced hypertension in familial dysautonomia. Clin Auton Res 26, 79–81 (2016). https://doi.org/10.1007/s10286-015-0323-9

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  • DOI: https://doi.org/10.1007/s10286-015-0323-9

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