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Recurrence of IgG4-related disease following treatment with rituximab

  • Case Report
  • Published:
Modern Rheumatology

Abstract

A 54-year-old woman with suspected low-grade B-cell lymphoma of mucosa-associated lymphoid tissue type of the eyelids underwent rituximab-containing chemotherapy. She initially responded to the rituximab therapy, but later experienced two recurrences over a 3-year period. Biopsy specimens and a review of her previous histology revealed that she had had immunoglobulin G4-related disease at the initial presentation. Although IgG4-related disease seems to respond well to rituximab therapy, long-term follow up, including disease monitoring, is needed to evaluate disease remission.

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Authors and Affiliations

  1. Department of Internal Medicine (3), Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan

    Jun Murakami, Kotaro Arita, Akinori Wada, Takayoshi Miyazono & Toshiro Sugiyama

  2. Department of Internal Medicine (1), Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama, 930-0194, Japan

    Shoko Matsui, Hiroyuki Hounoki, Koichiro Shinoda & Hirofumi Taki

  3. Department of Pathology, Toyama Prefectural Central Hospital, 2-2-78 Nishi-nagae, Toyama, 930-8550, Japan

    Shin Ishizawa

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  1. Jun Murakami
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  2. Shoko Matsui
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  3. Shin Ishizawa
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  4. Kotaro Arita
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  5. Akinori Wada
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  6. Takayoshi Miyazono
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  7. Hiroyuki Hounoki
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  8. Koichiro Shinoda
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  9. Hirofumi Taki
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  10. Toshiro Sugiyama
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Correspondence to Jun Murakami.

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Murakami, J., Matsui, S., Ishizawa, S. et al. Recurrence of IgG4-related disease following treatment with rituximab. Mod Rheumatol 23, 1226–1230 (2013). https://doi.org/10.1007/s10165-012-0738-2

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  • DOI: https://doi.org/10.1007/s10165-012-0738-2

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