Abstract
Glaucoma is the leading cause of irreversible blindness worldwide. The goal of this study was to describe our experience with the novel micropulse transscleral cyclophotocoagulation (MP-TSCPC; IRIDEX IQ810 Laser Systems, CA) in patients with advanced glaucoma. Patients with advanced glaucoma who underwent MP-TSCPC were included in our study. Laser settings were 2000 mW of 810 nm infrared diode laser set on micropulse delivery mode. The laser was delivered over 360° for 100–240 s. The duty cycle was 31.3 %, which translated to 0.5 ms of “on time” and 1.1 ms of “off time.” Surgical success was defined as an intraocular pressure (IOP) of 6–21 mmHg or a reduction of IOP by 20 % at the last follow-up visit. Failure was defined as an inability to meet the criteria for success or a need for incisional glaucoma surgery. Nineteen patients underwent MP-TSCPC with mean follow-up of 60.3 days. Mean IOP dropped from 37.9 mmHg preoperatively to 22.7 mmHg at last follow-up, representing a 40.1 % decrease. The success rate for initial treatment was 73.7 % (n = 14). Three patients underwent a second treatment, increasing the overall success rate to 89.5 % (n = 17). Four patients gained one line of vision, and four patients lost one line of vision. The novel MP-TSCPC laser had a high rate of surgical success after a short follow-up period in patients with advanced glaucoma. Further long-term evaluation and comparison to the traditional transscleral cyclophotocoagulation are warranted.
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Iridex Corporation provided the laser platform used in this study.
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All procedures performed in studies involving human participants were conducted in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. For this type of study (retrospective chart review), formal consent is not required.
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Drs. Moster, Kuchar, and Waisbourd received research support from Iridex. Dr. Moster is a consultant for Alcon, Allergan, Solx, and Merck; was an expert testimony case witness in 2013; has grants from Aerie, Aeon, New World Medical, Alcon, Glaukos, and Bausch and Lomb; and receives payment for lectures from Alcon, Allergan, Ista, Merck, Bausch and Lomb, New World Medical, TBI, and Solx. Courtney Reamer has no conflicts of interest to declare.
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Kuchar, S., Moster, M.R., Reamer, C.B. et al. Treatment outcomes of micropulse transscleral cyclophotocoagulation in advanced glaucoma. Lasers Med Sci 31, 393–396 (2016). https://doi.org/10.1007/s10103-015-1856-9
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DOI: https://doi.org/10.1007/s10103-015-1856-9