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Rare association of antiphospholipid syndrome and Takayasu arteritis

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Abstract

The antiphospholipid syndrome (APS) is characterized by obstetric and thrombotic complications in the presence of antiphospholipid antibodies. It can happen in an isolated way or in association with diffuse connective tissue diseases, mainly systemic lupus erythematosus. The association of APS with Takayasu arteritis (TA) is rarely described in the literature. We described a case of primary APS in a female patient who developed obstruction in large-size arteries, in spite of the use of oral anticoagulant, and increase of erythrocyte sedimentation rate, suggesting TA. The favorable response to prednisone treatment and later to infliximab reinforced the diagnosis of TA. The present report illustrates the existence of APS associated to TA, whose recognition is very important once the therapeutic strategy is radically different.

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Authors and Affiliations

  1. Escola Bahiana de Medicina e Saúde Pública, Núcleo de Reumatologia da Bahia no Hospital Santa Izabel, Salvador, Bahia, Brazil

    Mittermayer B. Santiago

  2. Hospital Universitário Professor Edgar Santos, Universidade Federal da Bahia, Salvador, Bahia, Brazil

    Otávio Paz

  3. Núcleo de Reumatologia do Hospital Santa Izabel, Praça Almeida Couto, 500, Nazaré, Salvador, Bahia, CEP 40.000-000, Brazil

    Mittermayer B. Santiago

Authors
  1. Mittermayer B. Santiago
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  2. Otávio Paz
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Correspondence to Mittermayer B. Santiago.

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Santiago, M.B., Paz, O. Rare association of antiphospholipid syndrome and Takayasu arteritis. Clin Rheumatol 26, 821–822 (2007). https://doi.org/10.1007/s10067-006-0277-3

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  • DOI: https://doi.org/10.1007/s10067-006-0277-3

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