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“Proximal-type” and Classic Epithelioid Sarcomas Represent a Clinicopathologic Continuum: Case Report

  • CASE REPORT
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Pediatric and Developmental Pathology

Abstract

We report a case of an epithelioid sarcoma that occurred in the right hand of a 14−year-old boy and had the “proximal-type” morphology and a complex, near-tetraploid karyotype. The tumor metastasized to the lungs, where the morphology was typical for the classic epithelioid sarcoma. Based on the morphologic and cytogenetic findings in this case, we suggest that the proximal-type and the classic epithelioid sarcomas are not distinct entities but represent a continuum.

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Acknowledgments

The authors thank the technical staff at ProPath Laboratory, Inc. (Dallas, TX) for excellent immunohistochemical work and Jeff Dolittle, chief technologist at the cytogenetics laboratory at Veripath Laboratories (Dallas, TX), for excellent technical help with conventional and molecular cytogenetics.

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Authors and Affiliations

  1. Department of Pathology, Children’s Medical Center of Dallas, 1935 Motor Street, Dallas, TX, 75235, USA

    Dinesh Rakheja & Ana M. Gomez

  2. Department of Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX, 75390, USA

    Dinesh Rakheja, Kathleen S. Wilson, Roger A. Schultz & Ana M. Gomez

  3. Department of Radiology, Children’s Medical Center of Dallas, 1935 Motor Street, Dallas, TX, 75235, USA

    John Meehan

Authors
  1. Dinesh Rakheja
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  2. Kathleen S. Wilson
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  3. John Meehan
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  4. Roger A. Schultz
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  5. Ana M. Gomez
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Corresponding author

Correspondence to Ana M. Gomez.

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Rakheja, D., Wilson, K.S., Meehan, J. et al. “Proximal-type” and Classic Epithelioid Sarcomas Represent a Clinicopathologic Continuum: Case Report. Pediatr Dev Pathol 8, 105–114 (2005). https://doi.org/10.1007/s10024-004-7086-y

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  • DOI: https://doi.org/10.1007/s10024-004-7086-y

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