Original Article

Clinical Oral Investigations

, Volume 18, Issue 1, pp 239-246

First online:

Globulomaxillary cysts—do they really exist?

  • U. DammerAffiliated withDepartment of Oral and Maxillofacial Surgery, University of Regensburg Email author 
  • , O. DriemelAffiliated withDepartment of Oral and Maxillofacial Surgery, University of Regensburg
  • , W. MohrenAffiliated withInstitute of Pathology, Hospital Deggendorf
  • , C. GiedlAffiliated withInstitute of Pathology, University of Regensburg
  • , T. E. ReichertAffiliated withDepartment of Oral and Maxillofacial Surgery, University of Regensburg

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The so-called “globulomaxillary cyst”, described as a fissural cyst, caused by entrapped epithelium between the nasal and maxillary process, is no longer considered for its own entity. Nevertheless, cystic lesions, which correspond to the previous image of globulomaxillary cysts, do still occur in daily practice. This raises the question to which entities pathological processes in this particular region actually belong to.

Materials and methods

In a retrospective study, 17 cases (12 men and 5 women, 12–59 years old) of primarily diagnosed globulomaxillary cysts are analysed according to clinical, radiological and histological aspects, catamnestic processed and assigned to a new entity. The results are compared with the international literature and draws conclusions on the diagnostic and therapeutic procedure.


Seven lateral periodontal cysts, four radicular cysts, two keratocystic odontogenic tumours, one adenomatoid odontogenic tumour, one periapical granuloma, one residual cyst and one undefined jaw cyst were determined.


According to the results of our study and the data from the international literature, the entity globulomaxillary cyst is no longer justified.


Globulomaxillary cyst Jaw cysts WHO Classification Epithelial odontogenic tumour Diagnostic pitfall