Journal of Bone and Mineral Metabolism

, Volume 25, Issue 2, pp 114–121

Establishment of peak bone mineral density in Southern Chinese males and its comparisons with other males from different regions of China

Authors

  • Li-Jun Tan
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
  • Shu-Feng Lei
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
  • Xiang-Ding Chen
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
  • Man-Yuan Liu
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
  • Yan-Fang Guo
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
  • Hong Xu
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
  • Xiao Sun
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
  • Cheng Jiang
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
  • Su-Mei Xiao
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
  • Jing-Jing Guo
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
  • Yan-Jun Yang
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
  • Fei-Yan Deng
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
  • Yan-Bo Wang
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
  • Yuan-Neng Li
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
  • Xue-Zhen Zhu
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
    • Laboratory of Molecular and Statistical Genetics and the Key Laboratory of Protein Chemistry and Developmental Biology of Ministry of Education, College of Life SciencesHunan Normal University
    • Department of Orthopedic Surgery, School of MedicineUniversity of Missouri-Kansas City
    • Laboratory of Molecular and Statistical Genetics, College of Life SciencesHunan Normal University
ORIGINAL ARTICLE

DOI: 10.1007/s00774-006-0737-5

Cite this article as:
Tan, L., Lei, S., Chen, X. et al. J Bone Miner Metab (2007) 25: 114. doi:10.1007/s00774-006-0737-5

Abstract

Peak bone mineral density (PBMD) is an important determinant of osteoporotic fracture and a precondition for correct diagnosis of osteoporosis. The objective of this study was to establish the reference data of PBMD at the lumber spine and hip in Southern Chinese males. Bone mineral density (BMD) was measured at the lumbar spine and hip (femoral neck, trochanter, intertrochanter, and total) in 1155 Chinese men aged 15–39 years, using dual-energy X-ray absorptiometry (DXA). We utilized a fit curve method to determine the best age range over which to calculate PBMD. Our results indicated that the PBMD was observed at the age range of 18–25 years at the various sites. The mean value and standard deviation of PBMD was 0.753 ± 0.117, 1.156 ± 0.148, 0.896 ± 0.120, 0.989 ± 0.122, and 0.980 ± 0.116 g/cm2 at the trochanter, intertrochanter, femoral neck, total hip, and spine, respectively. When the present PBMD reference was compared with the documented PBMD reference of males from other regions of China, we found great difference in standardized PBMD between Changsha males and those from other regions of China. The PBMD for Chinese males in Changsha at the various sites were 3.19%–11.33% lower than that for American Caucasian males. In conclusion, the PBMD at the spine and hip may be used as normal reference data for Southern Chinese males in Changsha instead of documented PBMD from other regions of China and the manufacturer's reference data.

Key words

Chinese malegeographic differencepeak bone mineral densityreference data
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Copyright information

© Springer-Verlag Tokyo 2007