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Surgery for peripapillar choroidal neovascularization

Chirurgische Therapie parapapillärer choroidaler Neovaskularisationen

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Zusammenfassung

Die Therapie der choroidalen Neovascularisation (CNV) bei Patienten mit feuchter Makuladegeneration entwickelte sich zur Anti-VEGF Therapie. Die peripapilläre CNV (PPCNV) ist eine andere Manifestation der CNV, die zusätzlich mittels chirurgischer Entfernung der Membranen behandelt werden kann. METHODIK: In dieser retrospektiven Studie wurde in 9 Augen von 9 Patienten evaluiert, ob es zu einer Verbesserung der morphologischen und visuellen Befunde durch die Operation kommt. RESULTATE: Die Operation war erfolgreich bei allen Patienten und das Sehvermögen blieb stabil oder verbesserte sich bei jedem Patienten um 2 oder mehr Linien. DISKUSSION: Folglich könnte die operative Entfernung der Membranen einen alternativen Ansatz in der Therapie von PPCNVs darstellen, obwohl nur eine kleine Anzahl an Patienten untersucht wurde. Randomisierte prospektive Studien sind erforderlich, die den Effekt von Operation oder Anti-VEGF Therapie allein oder in Kombination evaluieren.

Summary

The therapy of choroidal neovascularizations (CNVs) in wet age-related macular degeneration (AMD) developed to an anti-vascular endothelial growth factor (VEGF) therapy. Peripapilar CNV (PPCNV) represents another manifestation of CNV which may treated additionally by surgical extraction of the membranes. METHODS: In this retrospective study, the morphological and visual outcome after surgery of 9 eyes of 9 patients with PPCNV was evaluated. RESULTS: Surgery was successful in each patient and visual acuity remaind stable or improved in each patient by two or more lines. Recurrence was observed in 6 eyes within three years. DISCUSSION: Hence, surgery may represent an alternative approach in the therapy of PPCNV although only a small number of cases were included. Randomized prospective trials comparing surgical excision of PPCNV with anti-VEGF therapy alone or in combination are needed.

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Authors and Affiliations

  1. Department of Opthalmology and Optometry, Medical University of Innsbruck, Innsbruck, Austria

    J. Troger, M. Kralinger & G. Kieselbach

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  1. J. Troger
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  2. M. Kralinger
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  3. G. Kieselbach
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Correspondence to G. Kieselbach.

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Troger, J., Kralinger, M. & Kieselbach, G. Surgery for peripapillar choroidal neovascularization. Spektrum Augenheilkd. 22, 362–364 (2008). https://doi.org/10.1007/s00717-008-0295-4

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