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Synthesis and biological evaluation of some novel indole analogues containing triazolopyrimidine moiety

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Abstract

To examine new leads with potent antimicrobial and antioxidant activities, in this study, new indole analogues containing triazolopyrimidine moiety are synthesized and their structures have been established on the basis of their spectral studies and elemental analyses. These compounds were evaluated for their in vitro antimicrobial and antioxidant activities. Some of the compounds revealed good antimicrobial and antioxidant activity.

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Acknowledgements

The authors are thankful to the Chairman, Department of Chemistry, Gulbarga University, Gulbarga for providing laboratory facilities; to the Chairman, Department of Microbiology, Gulbarga University, Gulbarga for providing facilities to carry out antimicrobial activity and to the Chairman, Department of Material Science, Gulbarga University, Gulbarga for providing IR spectra. Also thankful to the Director, CIL, Panjab University, Chandigarh and to the Director, Indian Institute Of Technology, Madras, Chennai for providing spectral data.

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Authors and Affiliations

  1. Department of Post-Graduate Studies and Research in Chemistry, Gulbarga University, Gulbarga, 585 106, Karnataka, India

    Anand R. Saundane, Annapurna Halu & N. M. Kirankumar

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  1. Anand R. Saundane
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  2. Annapurna Halu
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  3. N. M. Kirankumar
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Correspondence to Anand R. Saundane.

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Saundane, A.R., Halu, A. & Kirankumar, N.M. Synthesis and biological evaluation of some novel indole analogues containing triazolopyrimidine moiety. Monatsh Chem 148, 1497–1511 (2017). https://doi.org/10.1007/s00706-017-1957-1

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  • DOI: https://doi.org/10.1007/s00706-017-1957-1

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