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A diastereoselective synthesis of (Z)-3-[(aryl)(hydroxyimino)methyl]-2-cyclohexyl-1-(cyclohexylamino)imidazo[5,1-a]isoquinolinium chlorides from isoquinoline, chlorooximes, and cyclohexyl isocyanide

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Abstract

A novel diastereoselective synthesis of (Z)-3-[(aryl)(hydroxyimino)methyl]-2-cyclohexyl-1-(cyclohexylamino)imidazo[5,1-a]isoquinolinium chlorides has been described by a simple condensation of isoquinoline, aryl chlorooximes, and cyclohexyl isocyanide at room temperature.

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Acknowledgments

We acknowledge the financial support of Islamic Azad University, Bushehr Branch.

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Authors and Affiliations

  1. Chemistry Department, Islamic Azad University, Bushehr Branch, Bushehr, Iran

    Gholamhossein Khalili

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  1. Gholamhossein Khalili
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Correspondence to Gholamhossein Khalili.

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Khalili, G. A diastereoselective synthesis of (Z)-3-[(aryl)(hydroxyimino)methyl]-2-cyclohexyl-1-(cyclohexylamino)imidazo[5,1-a]isoquinolinium chlorides from isoquinoline, chlorooximes, and cyclohexyl isocyanide. Monatsh Chem 147, 429–433 (2016). https://doi.org/10.1007/s00706-015-1522-8

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  • DOI: https://doi.org/10.1007/s00706-015-1522-8

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