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Detection strategies of tick-borne encephalitis virus in Swedish Ixodes ricinus reveal evolutionary characteristics of emerging tick-borne flaviviruses

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Summary.

The flaviviral tick-borne encephalitis virus (TBEV) is a human pathogen having significant impact on public health. The geographical distribution of TBEV and TBEV-like viruses is increasing, which makes it important to characterise the natural virus populations. Here we present four RT-PCR strategies designed for detection of broad types of tick-borne flaviviruses. Sequence information on more than 32% of a TBEV genome was generated from a small pool of ticks collected in the Stockholm archipelago on the island of Torö. The sequences were characterised and compared with those of other tick-borne flaviviruses, which classified the virus as Western European TBEV.

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Authors and Affiliations

  1. School of Life Sciences, Södertörns University College, Huddinge, Sweden

    W. Melik & M. Johansson

  2. Department of Genetics, Microbiology and Toxicology, Stockholm University, Stockholm, Sweden

    W. Melik & A. S. Nilsson

Authors
  1. W. Melik
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  2. A. S. Nilsson
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  3. M. Johansson
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Melik, W., Nilsson, A. & Johansson, M. Detection strategies of tick-borne encephalitis virus in Swedish Ixodes ricinus reveal evolutionary characteristics of emerging tick-borne flaviviruses. Arch Virol 152, 1027–1034 (2007). https://doi.org/10.1007/s00705-006-0922-9

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  • DOI: https://doi.org/10.1007/s00705-006-0922-9

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