Clinical Article

Acta Neurochirurgica

, Volume 154, Issue 3, pp 509-515

Assessment of non-motor hearing symptoms in hemifacial spasm using magnetoencephalography

  • Young Seok ParkAffiliated withDepartment of Neurosurgery, Yonsei University College of MedicineDepartment of Neurosurgery, Bundang CHA Medical Center, CHA University
  • , Bong Soo KimAffiliated withDepartment of Neurosurgery, Yonsei University College of Medicine
  • , Dong Kyu LeeAffiliated withDepartment of Neurosurgery, Yonsei University College of Medicine
  • , Seung-Koo LeeAffiliated withDepartment of Radiology, Severance Hospital, MEG Center, Severance Hospital Brain Korea 21 Project for Medical Science, Brain Research Institute, Yonsei University College of Medicine
  • , Hyuk Chan KwonAffiliated withCenter for Brain and Cognitive Science Research, Korea Research Institute of Standards and Science
  • , Kiwoong KimAffiliated withCenter for Brain and Cognitive Science Research, Korea Research Institute of Standards and Science
  • , Yong Ho LeeAffiliated withCenter for Brain and Cognitive Science Research, Korea Research Institute of Standards and Science
  • , Jin Woo ChangAffiliated withDepartment of Neurosurgery, Yonsei University College of Medicine Email author 

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Abstract

Background

Hemifacial spasm patients often suffer from non-motor symptoms such as tinnitus. These non-motor symptoms are known to be associated with changes in cortical activity. Magnetoencephalography (MEG) is a technique that can record brain activity noninvasively. To determine the usefulness of MEG in assessing changes in cortical activity associated with non-motor hearing symptoms in hemifacial spasm patients.

Methods

We used MEG to evaluate the reactivity of the auditory cortex in 26 hemifacial spasm patients. We divided patients into a subjective tinnitus group (n = 10) and a non-tinnitus group (n = 16). The latency and amplitude of the most prominent deflection, N100m, was compared between the two groups.

Results

There was a significant difference in the pure tone audiogram on the spasm side compared with the non-spasm side. After stimulation on the spasm side, the amplitude of the N100m peak in the contralateral hemisphere was lower in the subjective tinnitus group than in the non-tinnitus group.

Conclusions

Our results indicate that MEG can detect differences in cortical activity between hemifacial spasm patients with and without tinnitus. This suggests that MEG can identify changes in cortical activity associated with non-motor symptoms.

Keywords

Dysynchronization Hearing Hemifacial spasm MEG