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Status and perspectives of neuroprotective therapies in glaucoma: The European Glaucoma Society White Paper

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Abstract

Glaucoma, a chronic progressive neuropathy and the most frequent cause of irreversible blindness worldwide, is commonly treated by medication or surgery aimed at lowering intraocular pressure. In view of the limited therapeutic options, the European Glaucoma Society (EGS) sponsored two Think Tank Meetings with the goal of assessing the current status and the overall perspectives for neuroprotective treatment strategies in glaucoma. The results of the meetings are summarized in this EGS White Paper.

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Acknowledgments

The authors thank David Garway-Heath and Michael Bach for critically reading drafts of this manuscript and for providing extremely helpful comments. We also greatly appreciate invaluable insights and considerations from the European Glaucoma Society Think Tank participants:

Raffaella Aldigeri, University of Parma, Italy

Eleftherios Anastasopoulos, University of Thessaloniki, Greece

Michael Bach, University of Freiburg, Germany

Daniele Bottai, University of Milan, Italy

Helmut Brandstätter, University of Erlangen-Nürnberg, Germany

Francesca Cordeiro, Institute of Ophthalmology, London, UK

Alexandre Denoyer, INSERM, UPMC, University Paris, France

Dietmar Fischer, University of Düsseldorf, Germany

Paolo Fogagnolo, University of Milan, Italy

Mike Francke, University of Leipzig, Germany

Rudolf Fuchshofer, University of Regensburg, Germany

Stefano Gandolfi, University of Parma, Italy

David Garway-Heath, Moorfields Eye Hospital, London, UK

Franz Grehn, University of Würzburg, Germany

Franz Grus, University of Mainz, Germany

Michele Iester, University of Genoa, Italy

Mike Karl, University of Dresden, Germany

Jan Kremers, University of Erlangen-Nürnberg, Germany

Kerstin Krieglstein, University of Freiburg, Germany

Gerassimos Lascaratos, Moorfields Eye Hospital, London, UK

Eduardo Normando, Institute of Ophthalmology, London, UK

Andreas Ohlmann, University of Regensburg, Germany

Iok-Hou Pang, University of North Texas Health Science Center, TX

Norbert Pfeiffer, University of Mainz, Germany

Franziska Rauscher, University of Leipzig, Germany

Luca Mario Rossetti, University of Milan, Italy

Günther Schlunck, University of Freiburg, Germany

Leopold Schmetterer, Medical University of Vienna, Austria

Hagen Thieme, University of Magdeburg, Germany

Ernst R. Tamm, University of Regensburg, Germany

Fotis Topouzis, University of Thessaloniki, Greece

Klaus Unsicker, University of Freiburg, Germany

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Correspondence to Ernst R. Tamm.

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The Think Tank Meetings were fully supported by the European Glaucoma Society.

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Tamm, E.R., Schmetterer, L. & Grehn, F. Status and perspectives of neuroprotective therapies in glaucoma: The European Glaucoma Society White Paper. Cell Tissue Res 353, 347–354 (2013). https://doi.org/10.1007/s00441-013-1637-3

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