Abstract
We report a case of erythema annulare centrifugum (EAC) with neonatal onset. The patient presented on the fourth day of life with erythematous papules that enlarged centrifugally to form annular or policyclic plaques on anterior surface of trunk and legs without signs of systemic toxicity. Subsequently, she developed sepsis and disseminated intravascular coagulation and died on the sixth day of life. Blood culture grew Pseudomonas aeruginosa. The coexistence of P. aeruginosa sepsis with the clinical appearance of erythema annulare centrifugum strongly suggests a pathogenetic effect of the microorganism on the skin eruption. To the best of our knowledge, this is the first report of EAC with P. aeruginosa sepsis in a newborn.
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Bottoni U, Innocenzi D, Pl B et al (2002) Erythema annulare centrifugum: report of a case with neonatal onset. J Eur Acad Dermatol Venereol 16:500–503
Burgdorf WHC (1999) Erythema annulare centrifugum and other figurate erythemas. In: Freedberg IM, Eisen AZ, Wolff K, Katz SI, Goldsmith LA, Austen KF, Fitzpatrick TB (eds) Fitzpatrick’s Dermatology in general medicine, 5th edn. McGraw Hill, New York, pp 1149–1152
Czechowicz RT, Warren LJ, Moore L, Saxon B (2001) Pseudomonas aeruginosa infection mimicking erythema annulare centrifugum. Australas J Dermatol 42:57–59
Hammar H (1974) Erythema annulare centrifugum coincident with Epstein–Barr virus infection in an infant. Acta Paediatr Scand 63:788–792
Hsu S, Le EH, Khoshevis MR (2001) Differential diagnosis of annular lesions. Am Fam Physician 64:289–296
Kanj SS, Sexton DJ (2012) Pseudomonas aeruginosa skin, soft tissue, and bone infections. In: Sexton DJ, Bloom A (eds) UpToDate. Waltham, MA
Kim KJ, Chang SE, Choi JH, Sung KJ, Moon KC, Koh JK (2002) Clinicopathologic analysis of erythema annulare centrifugum. J Dermatol 29:61–67
Nizet V, Klein JO (2011) Bacterial sepsis and meningitis. In: Remington JS, Klein JO, Wilson CB, Nizet V, Maldonado YA (eds) Infectious diseases of the fetus and newborn infant, 7th edn. Elsevier Saunders, Philadelphia, p 232
Rani Z, Rashid T, Hussain I (2003) Erythema annulare centrifugum in association with hypothyroidism: a case report. J Pak Med Assoc 13:89–91
Tyring SK (1993) Reactive erythemas: erythema annulare centrifugum and erythema gyratum repens. Clin Dermatol 11:135–139
Weyers W, Diaz-Cascajo C, Weyers I (2003) Erythema annulare centrifugum: results of a clinicopathologic study of 73 patients. Am J Dermatopathol 25:451–462
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Kavurt, S., Aydemir, O., Celik, U. et al. Erythema annulare centrifugum as the presenting sign of Pseudomonas aeruginosa sepsis in a newborn. Eur J Pediatr 172, 847–849 (2013). https://doi.org/10.1007/s00431-012-1848-8
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DOI: https://doi.org/10.1007/s00431-012-1848-8