Short Report

European Journal of Pediatrics

, Volume 169, Issue 12, pp 1549-1551

Too much of too little: xylitol, an unusual trigger of a chronic metabolic hyperchloremic acidosis

  • David WilleAffiliated withDepartment of Intensive Care and Neonatology, University Children’s Hospital
  • , Mathias Hauri-HohlAffiliated withDepartment of Intensive Care and Neonatology, University Children’s Hospital
  • , Priska VonbachAffiliated withDepartment of Hospital Pharmacy, University Children’s Hospital
  • , Maren TomaskeAffiliated withDepartment of Pediatrics, Triemli Hospital Zurich
  • , Beth PaddenAffiliated withDepartment of Intensive Care and Neonatology, University Children’s Hospital
  • , Vera BernetAffiliated withDepartment of Intensive Care and Neonatology, University Children’s Hospital Email author 

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Abstract

Homeopathic globules are frequently used in children as a first-line treatment. Most of these globules are coated with sugar substitutes like xylitol; these substitutes are known for their laxative effect. Our patient shows that consumption of globules coated with xylitol does not have only laxative effects. It may cause indeed considerable weight loss and life-threatening enteral bicarbonate loss by diarrhea when overdosed in an infant.

Keywords

Children Metabolic acidosis Xylitol Enteral bicarbonate loss