Skip to main content
SpringerLink
Log in

Atypical teratoid/rhabdoid tumor in the sella turcica of an elderly female with a distinct vascular pattern and genetic alterations

  • Brief Report
  • Published:
Virchows Archiv Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

References

  1. Judkins AR, Eberhart CG, Wesseling P, Hasselblatt M (2016) Atypical teratoid/rhabdoid tumour. In: Louis DN, Ohgaki H, Wiestler OD, Cavenee WK (eds) World Health Organization classification of tumours of the central nervous system, revised, 4th edn. IARC Press, Lyon, pp. 209–212

    Google Scholar 

  2. Biegel JA (2006) Molecular genetics of atypical teratoid/rhabdoid tumor. Neurosurg Focus 20:E11

    Article  PubMed  Google Scholar 

  3. Sinha P, Ahmad M, Varghese A, et al. (2015) Atypical teratoid rhabdoid tumour of the spine: report of a case and literature review. Eur Spine J 24:S472–S484

    Article  PubMed  Google Scholar 

  4. Raisanen J, Biegel JA, Hatanpaa KJ, Judkins A, White CL, Perry A (2005) Chromosome 22q deletions in atypical teratoid/rhabdoid tumors in adults. Brain Pathol 15:23–28

    Article  CAS  PubMed  Google Scholar 

  5. Moretti C, Lupoi D, Spasaro F, et al. (2013) Sella turcica atypical teratoid/rhabdoid tumor complicated with lung metastasis in an adult female. Clin Med Insights Case Rep 6:177–182

    PubMed  PubMed Central  Google Scholar 

  6. Shitara S, Akiyama Y (2014) Atypical teratoid/rhabdoid tumor in sellar turcica in an adult: a case report and review of the literature. Surg Neurol Int 5:75

    Article  PubMed  PubMed Central  Google Scholar 

  7. Park HG, Yoon JH, Kim SH, et al. (2014) Adult-onset sellar and suprasellar atypical teratoid rhabdoid tumor treated with a multimodal approach: a case report. Brain Tumor Res Treat 2:108–113

    Article  PubMed  PubMed Central  Google Scholar 

  8. Biswas S, Wood M, Joshi A, et al. (2015) Exome sequencing of an adult pituitary atypical teratoid rhabdoid tumor. Front Oncol 5:236

    Article  PubMed  PubMed Central  Google Scholar 

  9. Las Heras F, Pritzker KP (2010) Adult variant of atypical teratoid/rhabdoid tumor: immunohistochemical and ultrastructural confirmation of a rare tumor in the sella tursica. Pathol Res Pract 206:788–791

    Article  PubMed  Google Scholar 

  10. Nobusawa S, Hirato J, Sugai T, et al. (2016) Atypical teratoid/rhabdoid tumor (AT/RT) arising from ependymoma: a type of AT/RT secondarily developing from other primary central nervous system tumors. J Neuropathol Exp Neurol 75:167–174

    Article  PubMed  Google Scholar 

  11. Ammerlaan AC, Ararou A, Houben MP, et al. (2008) Long-term survival and transmission of INI1-mutation via nonpenetrant males in a family with rhabdoid tumour predisposition syndrome. Br J Cancer 98:474–479

    Article  CAS  PubMed  Google Scholar 

  12. Eaton KW, Tooke LS, Wainwright LM, Judkins AR, Biegel JA (2011) Spectrum of SMARCB1/INI1 mutations in familial and sporadic rhabdoid tumors. Pediatr Blood Cancer 56:7–15

    Article  PubMed  PubMed Central  Google Scholar 

  13. Bruggers CS, Bleyl SB, Pysher T, et al. (2011) Clinicopathologic comparison of familial versus sporadic atypical teratoid/rhabdoid tumors (AT/RT) of the central nervous system. Pediatr Blood Cancer 56:1026–1031

    Article  PubMed  Google Scholar 

  14. Bourdeaut F, Lequin D, Brugières L, et al. (2011) Frequent hSNF5/INI1 germline mutations in patients with rhabdoid tumor. Clin Cancer Res 17:31–38

    Article  CAS  PubMed  Google Scholar 

  15. Biegel JA, Busse TM, Weissman BE (2014) SWI/SNF chromatin remodeling complexes and cancer. Am J Med Genet C Semin Med Genet 166C:350–366

    Article  PubMed  Google Scholar 

  16. Johann PD, Erkek S, Zapatka M, et al. (2016) Atypical teratoid/rhabdoid tumors are comprised of three epigenetic subgroups with distinct enhancer landscapes. Cancer Cell 29:379–393

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgments

We thank Ms. Machiko Yokota and Mr. Tatsuya Yamazaki (Gunma University) for their excellent technical assistance.

Author information

Authors and Affiliations

  1. Department of Human Pathology, Gunma University Graduate School of Medicine, 3-39-22, Showa-machi, Maebashi, Gunma, 371-8511, Japan

    Sumihito Nobusawa, Satoshi Nakata, Hayato Ikota & Hideaki Yokoo

  2. Department of Pathology, Gunma University Hospital, Maebashi, Japan

    Junko Hirato

  3. Department of Neurosurgery, Maebashi Red-Cross Hospital, Maebashi, Japan

    Takahiro Kawashima, Koji Sato & Hiroya Fujimaki

  4. Department of Radiology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan

    Naoki Okura

Authors
  1. Sumihito Nobusawa
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Satoshi Nakata
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Junko Hirato
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Takahiro Kawashima
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Koji Sato
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Hiroya Fujimaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Naoki Okura
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Hayato Ikota
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Hideaki Yokoo
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Sumihito Nobusawa.

Ethics declarations

This case study was conducted in accordance with the Ethics Committee of Gunma University.

Conflict of interest

The authors declare that they have no conflict of interest.

Funding

This study was not supported by any funding.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Nobusawa, S., Nakata, S., Hirato, J. et al. Atypical teratoid/rhabdoid tumor in the sella turcica of an elderly female with a distinct vascular pattern and genetic alterations. Virchows Arch 469, 711–715 (2016). https://doi.org/10.1007/s00428-016-2017-7

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00428-016-2017-7

Keywords

Search

Navigation