Notes
A confounder or confounding variable correlates with both the outcome and the risk factor investigated. For example, given a dose of radiation and an outcome, in the form of an excess risk at a given dose level, then a variable is a confounder if it is correlated with both the outcome and the dose.
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Acknowledgments
We would like to thank Dr. Ronald E.J. Mitchel, Atomic Energy of Canada Limited, Chalk River Laboratories, for revising the manuscript. The research leading to these results has received funding from the Euratom Seventh Framework Program under grant agreement n° 295823 (PROCARDIO). This report makes use of data obtained from the Radiation Effects Research Foundation (RERF) in Hiroshima, Japan. RERF is a private, non-profit foundation funded by the Japanese Ministry of Health, Labour and Welfare (MHLW) and the US Department of Energy (DOE), the latter through the National Academy of Sciences. The conclusions in this report are those of the authors and do not necessarily reflect the scientific judgment of RERF or its funding agencies.
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Schöllnberger, H., Kaiser, J.C., Walsh, L. et al. Reply to Little et al.: dose–responses from multi-model inference for the non-cancer disease mortality of atomic bomb survivors. Radiat Environ Biophys 52, 161–163 (2013). https://doi.org/10.1007/s00411-012-0454-5
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DOI: https://doi.org/10.1007/s00411-012-0454-5