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Weitere Belege für initiale subkutane Applikation von MTX in der Therapie der rheumatoiden Arthritis gefordert

Further evidence necessary for initial subcutaneous administration of MTX in the treatment of rheumatoid arthritis

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The Original Article was published on 03 July 2018

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Literatur

  1. Braun J, Kästner P, Flaxenberg P et al (2008) Comparison of the clinical efficacy and safety of subcutaneous versus oral administration of methotrexate in patients with active rheumatoid arthritis: results of a six-month, multicenter, randomized, double-blind, controlled, phase IV trial. Arthritis Rheum 58:73–81

    Article  CAS  PubMed  Google Scholar 

  2. De Rotte MC, den Boer E, de Jong PH et al (2015) Methotrexate polyglutamates in erythrocytes are associated with lower disease activity in patients with rheumatoid arthritis. Ann Rheum Dis 74:408–414

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  3. Hazlewood GS, Thorne JC, Pope JE et al (2016) The comparative effectiveness of oral versus subcutaneous methotrexate for the treatment of early rheumatoid arthritis. Ann Rheum Dis 75:1003–1008

    Article  CAS  PubMed  Google Scholar 

  4. Schiff MH, Jaffe JS, Freundlich B et al (2014) Head-to-head, randomised, crossover study of oral versus subcutaneous methotrexate in patients with rheumatoid arthritis: drug-exposure limitations of oral methotrexate at doses ≥15 mg may be overcome with subcutaneous administration. Ann Rheum Dis 73:1549–1551

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Authors and Affiliations

  1. Schwerpunktpraxis internistische Rheumatologie, Sophienblatt 1, 24103, Kiel, Deutschland

    Pontus Harten

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  1. Pontus Harten
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Correspondence to Pontus Harten.

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P. Harten gibt an, dass kein Interessenkonflikt besteht.

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U. Müller-Ladner, Bad Nauheim

U. Lange, Bad Nauheim

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Harten, P. Weitere Belege für initiale subkutane Applikation von MTX in der Therapie der rheumatoiden Arthritis gefordert. Z Rheumatol 78, 382–384 (2019). https://doi.org/10.1007/s00393-019-0624-9

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  • DOI: https://doi.org/10.1007/s00393-019-0624-9

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