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Transradial catheterization may decrease the radial artery luminal diameter and impair the vasodilatation response in the access site at late term: an observational study

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Abstract

The present study aimed to evaluate the late-term changes in radial artery luminal diameter (RAD) and vasodilatation response following transradial catheterization (TRC). TRC-inducing trauma to radial artery intima may trigger chronic phase vascular changes and lead to anatomical and functional impairment. There is controversial data whether the impairment persists or repairs later. Fifty-six consecutive patients undergoing TRC were enrolled prospectively. Baseline RAD, flow-mediated dilatation (FMD) and nitroglycerin-mediated dilatation (NMD) of the radial artery at the access site were measured before TRC by high-resolution ultrasound. Six months later; RAD, FMD and NMD were measured again at the same access site. RAD at the sixth month was reduced compared with pre-procedural measurements (2.85 ± 0.44 versus 2.74 ± 0.42 mm, p = 0.0001).The average FMD decreased to 5.66 ± 5.87 %, which was significantly lower than the observed pre-procedural FMD (9.45 ± 5.01 %) 6 months after TRC (p = 0.0001). Likewise, the average NMD at the sixth month was reduced compared with pre-procedural NMD (9.52 ± 6.77 versus 6.64 ± 6.51 %, p = 0.018). Logistic regression analysis indicated that pre-procedural radial artery diameter to sheath size ratio was the independent predictor of NMD reduction (95 % confidence interval, β = −9.74, p = 0.024). TRC may lead to a significant luminal diameter reduction and impairment of vasodilatation response in the radial artery at late term.

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Authors and Affiliations

  1. Department of Cardiology, Acibadem University School of Medicine, Kerem Aydinlar Kampusu, Icerenkoy Mah. Kayisdagi Cad. No: 32, Ataşehir, Istanbul, Turkey

    Ali Buturak, Aleks Degirmencioglu & Sevket Gorgulu

  2. Department of Radiology, Acibadem Kadıkoy Hospital, Istanbul, Turkey

    Burak Murat Tekturk

  3. Department of Radiology, Acibadem University School of Medicine, Istanbul, Turkey

    Sila Ulus

  4. Department of Cardiology, Mehmet Akif Ersoy Thoracic and Cardiovascular Surgery Training and Research Hospital, Istanbul, Turkey

    Ozgur Surgit

  5. Department of Cardiovascular Surgery, Acibadem University School of Medicine, Istanbul, Turkey

    Cem Ariturk

  6. Department of Cardiology, Acıbadem Maslak Hospital, Istanbul, Turkey

    Ertugrul Zencirci

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  1. Ali Buturak
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  2. Burak Murat Tekturk
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  3. Aleks Degirmencioglu
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  4. Sila Ulus
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  5. Ozgur Surgit
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  7. Ertugrul Zencirci
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  8. Sevket Gorgulu
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Correspondence to Ali Buturak.

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Buturak, A., Tekturk, B.M., Degirmencioglu, A. et al. Transradial catheterization may decrease the radial artery luminal diameter and impair the vasodilatation response in the access site at late term: an observational study. Heart Vessels 31, 482–489 (2016). https://doi.org/10.1007/s00380-015-0640-x

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  • DOI: https://doi.org/10.1007/s00380-015-0640-x

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