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Heteroscedastic ANOVA: old p values, new views

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Abstract

The generalization of the Behrens–Fisher problem to comparing more than two means from nonhomogeneous populations has attracted the attention of statisticians for many decades. Several approaches offer different approximations to the distribution of the test statistic. The question of statistical properties of these approximations is still alive. Here, we present a brief overview of several approaches suggested in the literature and implemented in software with a focus on investigating the accuracy of p values as well as their dependence on nuisance parameters and on the underlying assumption of normality. We illustrate by simulation the behavior of p values. In addition to the Satterthwaite–Fai–Cornelius test, the Kenward–Roger test, the simple ANOVA F test, the parametric bootstrap test, and the generalized F test will be briefly discussed.

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References

  • Brown MB, Forsythe AB (1974) The small sample behavior of some statistics which test the equality of several means. Technometrics 16: 129–132

    Article  MATH  MathSciNet  Google Scholar 

  • Casella G, Berger RL (2002) Statistical inference, 2nd edn. Duxbury Press, Pacific Grove, CA

    Google Scholar 

  • Fai AHT, Cornelius PL (1996) Approximate F-tests of multiple degree of freedom hypotheses in generalized least squares analyses of unbalanced split-plot experiments. J Stat Comput Simul 54: 363–378

    Article  MATH  MathSciNet  Google Scholar 

  • Gamage J, Weerahandi S (1998) Size performance of some tests in one-way ANOVA. Commun Stat Simul Comput 27: 625–640

    Article  MATH  Google Scholar 

  • Giesbrecht FG, Burns JC (1985) Two-stage analysis based on a mixed model: large sample asymptotic theory and small sample simulation results. Biometrics 41: 477–486

    Article  MATH  Google Scholar 

  • Harville DA, Jeske DR (1992) Mean squared error of estimation or prediction under a general linear model. J Am Stat Assoc 87: 724–731

    Article  MATH  MathSciNet  Google Scholar 

  • Kackar RN, Harville DA (1984) Approximation for standard errors of estimators of fixed and random effects in mixed linear models. J Am Stat Assoc 79: 853–862

    Article  MATH  MathSciNet  Google Scholar 

  • Kenward MG, Roger JH (1997) Small sample inference for fixed effects from restricted maximum likelihood. Biometrics 53: 983–997

    Article  MATH  Google Scholar 

  • Krishnamoorthy K, Lu F, Mathew T (2007) A parametric bootstrap approach for ANOVA with unequal variances: Fixed and random models. Comput Stat Data Anal 51: 5731–5742

    Article  MATH  MathSciNet  Google Scholar 

  • LaMotte LR (2007) A direct derivation of the REML likelihood function. Stat Pap 48: 321–327

    Article  MATH  MathSciNet  Google Scholar 

  • Lee S, Ahn ChH (2003) Modified ANOVA for unequal variances. Commun Stat Simul Comput 32: 987–1004

    Article  MATH  MathSciNet  Google Scholar 

  • Rao CR, Kleffe J (1988) Estimation of variance components and applications. North-Holland, Amsterdam

    MATH  Google Scholar 

  • Satterthwaite FE (1941) Synthesis of variance. Psychometrika 6: 309–316

    Article  MATH  MathSciNet  Google Scholar 

  • Satterthwaite FE (1946) An approximate distribution of estimates of variance components. Biometrics Bull 2: 110–114

    Article  Google Scholar 

  • Tsui K-W, Weerahandi S (1989) Generalized p-values in significance testing of hypotheses in the presence of nuisance parameters. J Am Stat Assoc 84: 602–607

    Article  MathSciNet  Google Scholar 

  • Volaufova J, LaMotte LR (2008) Comparison of approximate tests of fixed effects in linear repeated measures design models with covariates. Tatra Mountains Mathematical Publications 39: 17–25

    MATH  MathSciNet  Google Scholar 

  • Weerahandi S (1995) ANOVA under unequal variances. Biometrics 51: 589–599

    Article  Google Scholar 

  • Welch BL (1951) On the comparison of several mean values: an alternative approach. Biometrika 38: 330–336

    MATH  MathSciNet  Google Scholar 

  • Xu L, Wang S (2008) A new generalized p-value and its upper bound for ANOVA under unequal error variances. Commun Stat Theory Methods 37: 1002–1010

    Article  MATH  Google Scholar 

Download references

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Correspondence to Julia Volaufova.

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Volaufova, J. Heteroscedastic ANOVA: old p values, new views. Stat Papers 50, 943–962 (2009). https://doi.org/10.1007/s00362-009-0262-4

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  • DOI: https://doi.org/10.1007/s00362-009-0262-4

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