Abstract
Purpose
To present our technique and outcomes for perineal urethrostomy augmented with a dorsal onlay buccal mucosa graft (BMG). Results from initial series and collaboration from an international center are included.
Methods
A retrospective chart review of all adult patients who underwent urethral reconstruction with perineal urethrostomy utilizing a buccal mucosal graft between January 1, 2002 and January 1, 2013 was performed. All surgeries were performed by three surgeons using the same technique (GHJ, KAM, and RV). Success was defined as no need for additional treatment following definitive surgery.
Results
A total of 44 patients met inclusion criteria. Mean patient age was 60 (range 44–81) years. All strictures were pananterior. Etiologies included unknown in 16 (36%), failed hypospadias repair in six (14%), lichen sclerosus in ten (23%), iatrogenic in seven (16%), Fournier’s in three (7%), urethral cancer in one (2%) and penile cancer in one (2%). Mean follow-up was 45 (range 6–136) months. Overall success was 80%. Nine patients recurred, of which four had a successful revision, two are awaiting potential revision, and three are being managed with periodic dilations.
Conclusions
BMG perineal urethrostomy is a valid alternative for complex urethral strictures due to lichen sclerosus, previous failed reconstructions or hypospadias cripples. Midterm results are encouraging for this novel technique.
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References
Santucci RA, Mario LA, McAninch JW (2002) Anastomotic urethroplasty for bulbar urethral stricture: analysis of 168 patients. J Urol 167:1715
Micheli E, Ranieri A Peracchia G, Lembo A (2002) End-to-end urethroplasty: long-term results. BJU Int 90:68
Andrich DE, Dunglison N, Greenwell TJ, Mundy AR (2003) The long-term results of urethroplasty. J Urol 170:90
Morey AF, Kizer WS (2006) Proximal bulbar urethroplasty via extended anastomotic approach: what are the limits? J Urol 175:2145
Eltahawy EA, Virasoro R, Schlossberg SM, McCammon KA, Jordan GH (2007) Long-term follow-up for excision and primary anastomosis for anterior urethral strictures. J Urol 177:1803
Andrich DE, Mundy AR (2001) Substitution urethroplasty with buccal mucosal-free grafts. J Urol 165(4):1131–1133
Dubey D, Mandhani KA, Srivastava A et al (2005) Buccal mucosa urethroplasty: a versatile technique for all urethral segments. BJU Int 95(4):625–629
Burger RA, Muller SC, el-Damanhoury H et al (1992) The buccal mucosal graft for urethral reconstruction: a preliminary report. J Urol 147(3):662–664
Castagnetti M, Rigamonti W (2009) Aptness and complications of labial mucosa grafts for the repair of anterior urethral defects in children and adults: single centre experience with 115 cases. World J Urol 27(6):799–803
Simonato A, Gregori A, Lissiani A et al (2006) The tongue as an alternative donor site for graft urethroplasty: a pilot study. J Urol 175:589–592
Myers JB, Porten SP, McAninch JW (2011) The outcomes of perineal urethrostomy with preservation of the dorsal urethral plate and urethral blood supply. Urology 77:1123–1227
Levine LA, Strom KH, Lux MM (2007) Buccal mucosa graft urethroplasty for urethral stricture repair: evaluation of the impact of stricture location and lichen sclerosus on surgical outcome. J Urol 178:2011–2015
Kulkarni S, Barbagli G, Kirpekar D et al (2009) Lichen sclerosus of the male genitalia and urethra: surgical options and results in a multicenter international experience with 215 patients. Eur Urol 55:945–954
Barbagli G, Perovic S, Djinovic R et al (2010) Retrospective descriptive analysis of 1,176 patients with failed hypospadias repair. J Urol 183:207–211
Dubey D, Sehgal A, Srivastava A et al (2005) Buccal mucosal urethroplasty for balanitis xerotica obliterans related urethral strictures: the outcome of 1 and 2-stage techniques. J Urol 173:463–466
Myers JB, McAninch JW (2011) Perineal urethrostomy. BJU Int 107(5):856–865
French D, Hudak SJ, Morey AF (2011) The “7-flap” perineal urethrostomy. Urology 77:1487–1490
Kamat N (2008) Perineal urethrostomy stenosis repair with buccal mucosa: description of technique and report of 4 cases. Urology 72:1153–1155
Davies TO, Bepple JL and Roseman T et al (2008) Perineal urethrostomy with buccal mucosal graft: a novel technique. J Urol 179(suppl 4):282
Morey AF, McAninch JW (1996) Technique of harvesting buccal mucosa for urethral reconstruction. J Urol 155(5):1696–1697
Palminteri E, Brandes SB, Djordjevic M (2012) Urethral reconstruction in lichen sclerosis. Curr Opin Urol 22(6):478–483
Kessler TM, Schreiter F, Kralidis G et al (2003) Long-term results of surgery for urethral stricture: a statistical analysis. J Urol 170:840–844
Peterson AC, Palminteri E, Lazzeri M et al (2004) Heroic measures may not always be justified in extensive urethral stricture due to lichen sclerosis (balanitis xerotica obliterans). Urology 64:565–568
Barbagli G, De Angelis M, Romano G et al (2009) Clinical outcome and quality of life assessment in patients treated with perineal urethrostomy for anterior urethral stricture disease. J Urol 182:548–557
Johanson B (1953) Reconstruction of the male urethra in strictures. Acta Chir Scand 173:1–88
Blandy JP, Singh M, Tresidder GC (1968) Urethroplasty by scrotal flap for long urethral strictures. BJU 40:261–267
Depasquale I, Park AJ, Bracka A (2000) The treatment of balanitis xeroticz obliterans. BJU Int 86:459–465
Pugliese JM, Morey AF, Peterson AC (2007) Lichen sclerosus: review of the literature and current recommendations for management. J Urol 178:2268–2276
Myers JB, McAninch JW, Erickson BA et al (2012) Treatment of adults with complications from previous hypospadias surgery. J Urol 188:459–463
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
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DeLong, J., McCammon, K., Capiel, L. et al. Augmented perineal urethrostomy using a dorsal buccal mucosal graft, bi-institutional study. World J Urol 35, 1285–1290 (2017). https://doi.org/10.1007/s00345-017-2002-z
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DOI: https://doi.org/10.1007/s00345-017-2002-z