Abstract
Objectives
To evaluate the heart rate lowering effect of relaxation music in patients undergoing coronary CT angiography (CCTA), pulmonary vein CT (PVCT) and coronary calcium score CT (CCS).
Methods
Patients were randomised to a control group (i.e. standard of care protocol) or to a relaxation music group (ie. standard of care protocol with music). The groups were compared for heart rate, radiation dose, image quality and dose of IV metoprolol. Both groups completed State-Trait Anxiety Inventory anxiety questionnaires to assess patient experience.
Results
One hundred and ninety-seven patients were recruited (61.9 % males); mean age 56y (19-86 y); 127 CCTA, 17 PVCT, 53 CCS. No significant difference in heart rate, radiation dose, image quality, metoprolol dose and anxiety scores. 86 % of patients enjoyed the music. 90 % of patients in the music group expressed a strong preference to have music for future examinations. The patient cohort demonstrated low anxiety levels prior to CT.
Conclusion
Relaxation music in CCTA, PVCT and CCS does not reduce heart rate or IV metoprolol use. Patients showed low levels of anxiety indicating that anxiolytics may not have a significant role in lowering heart rate. Music can be used in cardiac CT to improve patient experience.
Key Points
• Relaxation music does not reduce heart rate in cardiac CT
• Relaxation music does not reduce beta-blocker use in cardiac CT
• Relaxation music has no effect on cardiac CT image quality
• Low levels of anxiety are present in patients prior to cardiac CT
• Patients enjoyed the relaxation music and this results in improved patient experience
Similar content being viewed by others
Abbreviations
- CCS:
-
Coronary calcium score computed tomography
- CCTA:
-
Coronary computed tomography angiography
- CT:
-
Computed tomography
- DLP:
-
Dose length product
- DTA:
-
Descending thoracic aorta
- EW:
-
Exposure window
- HR:
-
Heart rate
- HRB :
-
Heart rate during final breathhold during ECG calibration
- HRI :
-
Heart rate during image acquisition
- HRI-W :
-
The change in heart rate between HRI and HRW
- HRT :
-
Heart rate on first arrival at the CT table
- HRW :
-
Heart rate in the waiting room prior to randomisation
- HU:
-
Hounsfield units
- kV:
-
Kilovoltage
- mA:
-
Milliampere
- MDCT:
-
Multidetector computed tomography
- PVCT:
-
Pulmonary vein computed tomography
- RRI:
-
ECG R-R interval
- STAI:
-
State-trait anxiety inventory
References
Halliburton SS, Abbara S, Chen MY et al (2011) SCCT guidelines on radiation dose and dose-optimization strategies in cardiovascular CT. J Cardiovasc Comput Tomogr 5:198–224
Jimenez-Juan L, Nguyen ET, Wintersperger BJ et al (2013) Failed heart rate control with oral metoprolol prior to coronary CT angiography: effect of additional intravenous metoprolol on heart rate, image quality and radiation dose. Int J Cardiovasc Imaging 29:199–206
Maffei E, Palumbo AA, Martini C et al (2009) "In-house" pharmacological management for computed tomography coronary angiography: heart rate reduction, timing and safety of different drugs used during patient preparation. Eur Radiol 19:2931–2940
Bradt J, Dileo C, Potvin N (2013) Music for stress and anxiety reduction in coronary heart disease patients (Review). The Cochrane Library
Chan MF, Wong OC, Chan HL et al (2007) Effect of music on patients undergoing a C-clamp procedure after percutaneous coronary interventions. J Adv Nurs 53:669–679
Cadigan ME, Caruso NA, Haldeman SM et al (2001) The effects of music on cardiac patients on bed rest. Prog Cardiovasc Nurs 16:5–13
Bernardi L, Porta C, Sleight P (2006) Cardiovascular, cerebrovascular, and respiratory changes induced by different types of music in musicians and non-musicians: the importance of silence. Heart 92:445–452
Barnason S, Zimmerman L, Nieveen J (1995) The effects of music interventions on anxiety in the patient after coronary artery bypass grafting. Heart Lung 24:124–132
De Loach Walworth D (2005) Procedural-support music therapy in the healthcare setting: a cost effectiveness analysis. J Pediatr Nurs 20:276–284
Marteau TM, Bekker H (1992) The development of a six-item short-form of the state scale of the Spielberger State-Trait Anxiety Inventory (STAI). Br J Clin Psychol 31:301–306
Tomizawa N, Maeda E, Akahane M, Torigoe R, Kiryu S, Ohtomo K (2013) Coronary CT angiography using the second-generation 320-detector row CT: assessment of image quality and radiation dose in various heart rates compared with the first-generation scanner. Int J Cardiovasc Imaging 29:1613–1618
van Hoe L, De Meerleer K, Leyman P, Vanhoenacker P (2003) Coronary artery calcium scoring using ECG-gated multidetector CT: effect of individually optimized image-reconstruction windows on image quality and measurement reproducibility. AJR 181:1093–1100
Korfage IJ, Essink-Bot ML, Janssens ACJW, Schroder FH, de Koning HJ (2006) Anxiety and depression after prostate cancer diagnosis and treatment: 5-year follow-up. Br J Cancer 94:1093–1098
Millar K, Jelicic M, Bonke B, Asbury AJ (1995) Assessment of preoperative anxiety: comparison of measures in patients awaiting surgery for breast cancer. Br J Anaesth 74:180–183
Ellis RJ, Thayer JF (2010) Music and autonomic nervous system (Dysfunction). Music Percept 27:317–326
Okada K, Kurita A, Takase B et al (2009) Effects of music therapy on autonomic nervous system activity, incidence of heart failure events, and plasma cytokine and cathecholamine levels in elderly patients with cerebrovascular disease and dementia. Int Heart J 50:95–110
Triposkiadis F, Karayannis G, Giamouzis G, Skoularigis J, Louridas G, Butler J (2009) The sympathetic nervous system in heart failure physiology, pathophysiology, and clinical implications. J Am Coll Cardiol 54:1747–1762
White JM (1992) Music therapy: an intervention to reduce anxiety in the myocardial infarction patient. Clin Nurse Specialist 6:58–63
Broscious S (1999) Music: an intervention for pain during chest tube removal after open heart surgery. Am J Crit Care 8:410–415
Chun EJ, Lee W, Choi YH et al (2008) Effects of nitroglycerin on diagnostic accuracy of electrocardiogram-gated coronary computed tomography angiography. J Comput Assist Tomogr 32:86–92
Decramer I, Vanhoenacker PK, Sarno G et al (2008) Effects of sublingual nitroglycerin on coronary lumen diameter and number of visualized septal branches on 64-MDCT angiography. AJR Am J Roentgenol 190:219–225
Okada M, Nakashima Y, Nomura T et al (2015) Coronary vasodilation by the use of sublingual nitroglycerin using 64-slice dual-source coronary computed tomography angiography. J Cardiol 65:230–236
Khan M, Cummings KW, Gutierrez FR, Bhalla S, Woodard PK, Saeed IM (2011) Contraindications and side effects of commonly used medications in coronary CT angiography. Int J Cardiovasc Imaging 27:441–449
Siedlecki SL (2009) Racial variation in response to music in a sample of african-american and caucasian chronic pain patients. Pain Manag Nurs 10:14–21
Good M, Bradford LP, Salem SG, Chin CC, Picot SF, Lane D (2000) Cultural differences in music chosen for pain relief. J Holist Nurs 18:245–260
Acknowledgments
The scientific guarantor of this publication is Elsie Thao Nguyen. The authors of this manuscript declare no relationships with any companies, whose products or services may be related to the subject matter of the article. This study has received funding by a Peter Munk Cardiac Centre Innovation Grant. Dr Ravi Menezes kindly provided statistical advice for this manuscript. Institutional Review Board approval was obtained. Written informed consent was obtained from all subjects (patients) in this study. Methodology: prospective, randomised controlled trial, performed at one institution.
Author information
Authors and Affiliations
Corresponding author
Electronic supplementary material
Below is the link to the electronic supplementary material.
ESM 1
(DOCX 23 kb)
Rights and permissions
About this article
Cite this article
Ng, M.Y., Karimzad, Y., Menezes, R.J. et al. Randomized controlled trial of relaxation music to reduce heart rate in patients undergoing cardiac CT. Eur Radiol 26, 3635–3642 (2016). https://doi.org/10.1007/s00330-016-4215-8
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00330-016-4215-8