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Cardiac involvement in juvenile idiopathic arthritis

  • Pathology Review
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Abstract

An insidious progression of cardiovascular (CV) involvement is generally associated with rheumatologic diseases and finally regarded as a major source of morbidity and mortality in Juvenile idiopathic arthritis (JIA) patients. JIA could involve all of the cardiac structures, including pericardium, myocardium, endocardium; coronary vessels; valves and conduction system. Development of pericarditis, myocarditis, endocarditis and ventricular dysfunction are not unexpected issues in the progress of JIA. It is essential to ensure a comprehensive follow-up with advanced and up-to-date diagnostic and therapeutic modalities for prevention of CV complications in JIA patients. Since these are all associated with an unfavorable prognosis, it is necessary to detect subclinical cardiac involvement in CV asymptomatic patients, in order to start adequate management and treatment. Furthermore, controlling chronic inflammatory state of JIA by new treatment modalities will also significantly reduce the overall morbidity and mortality related to CV diseases. In this review, we aimed to investigate CV involvement patterns in patients with JIA.

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Author contributions

OK designed the concept of paper. BK, OK and SS made the literature research and wrote the paper. AA and KB provided critical input in data collection and processing. All of the authors have analyzed the manuscript, finally.

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Authors and Affiliations

  1. Department of Pediatric Cardiology, Elazig Training and Research Hospital, Elazig, Turkey

    Bulent Koca

  2. Department of Pediatric Rheumatology, Cerrahpasa Medical School, Atakoy 1. Kisim D-43/8, 34750, Istanbul, Turkey

    Sezgin Sahin, Amra Adrovic, Kenan Barut & Ozgur Kasapcopur

Authors
  1. Bulent Koca
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  2. Sezgin Sahin
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  3. Amra Adrovic
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  4. Kenan Barut
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  5. Ozgur Kasapcopur
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Corresponding author

Correspondence to Ozgur Kasapcopur.

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This review was not funded by any person or corporation.

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The authors declare no conflict of interest.

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This article does not contain any studies with human participants or animals performed by any of the authors.

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Video 1

Color flow recording of a mitral and aortic regurgitation jet obtained from a zoomed view in the four chamber (AVI 4767 kb)

Video 2

Color flow recording of an aortic and mitral regurgitation jet obtained from a zoomed view in parasternal long axis chamber (AVI 5067 kb)

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Koca, B., Sahin, S., Adrovic, A. et al. Cardiac involvement in juvenile idiopathic arthritis. Rheumatol Int 37, 137–142 (2017). https://doi.org/10.1007/s00296-016-3534-z

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  • DOI: https://doi.org/10.1007/s00296-016-3534-z

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