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Y90-Radioembolization of Lung Metastases via the Bronchial Artery: A Report of 2 Cases

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Abstract

We report successful Y90-radioembolization of the lung applying Y90-resin microspheres via the bronchial artery in two patients with diffuse colorectal and renal cancer metastases, respectively. The deposition of radioactive Y90-resin-microspheres was technically feasible and resulted in a reasonable absorbed dose in the tumors. However, open questions remain regarding dosimetry and safe dose exposure to the lung. The technique warrants thorough investigation before clinical use. A Phase I trial to evaluate safety and preliminary efficacy is under preparation.

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Conflict of interest

Jens Ricke, Oliver Großer, and Holger Amthauer have received research grants as well as honoraria by Sirtex Inc.

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Authors and Affiliations

  1. Klinik für Radiologie und Nuklearmedizin, Universitätsklinikum Magdeburg AöR, Leipzigerstrasse 44, 39120, Magdeburg, Germany

    Jens Ricke, Oliver Großer & Holger Amthauer

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  1. Jens Ricke
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  2. Oliver Großer
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  3. Holger Amthauer
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Correspondence to Jens Ricke.

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Ricke, J., Großer, O. & Amthauer, H. Y90-Radioembolization of Lung Metastases via the Bronchial Artery: A Report of 2 Cases. Cardiovasc Intervent Radiol 36, 1664–1669 (2013). https://doi.org/10.1007/s00270-013-0690-3

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  • DOI: https://doi.org/10.1007/s00270-013-0690-3

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