Abstract
Impaired wound healing in the elderly presents a major clinical and economic problem. With the aging population growing in both number and percentage, the importance of understanding the mechanisms underlying age-related impairments in healing is increased. Normal skin exhibits characteristic changes with age that have implications for wound healing. Additionally, the process of wound healing is altered in aged individuals. Although historically healing in the aged was considered defective, there is now consensus that healing in the elderly is delayed but the final result is qualitatively similar to that in young subjects.
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This work was supported by grants GM50875 and GM55238 from the National Institutes of Health (NIH). A.G. is supported by the NIH T32-GM08750 Training Grant in Trauma and Burn Research.
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Gosain, A., DiPietro, L. Aging and Wound Healing. World J. Surg. 28, 321–326 (2004). https://doi.org/10.1007/s00268-003-7397-6
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DOI: https://doi.org/10.1007/s00268-003-7397-6