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Noninvasive Shock Wave Treatment for Capsular Contractures After Breast Augmentation: A Rabbit Study

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  • Experimental/Special Topics
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Abstract

Background

Capsular contracture is the most common complication of breast augmentation. Although numerous procedures are intended to prevent capsular contracture, their efficacy does not satisfy surgeons or patients. In the present study, we used shock waves to develop innovative protocols to treat capsular contracture in rabbits.

Methods

We used shock waves to treat capsular contracture in a rabbit model. Six clinical parameters were evaluated to determine the treatment efficacy of shock waves on the pathological histology of capsular contracture. Dual-flip-angle T1-mapping magnetic resonance imaging was used to confirm the pathological findings.

Results

Among the parameters, myxoid change, vascular proliferation, and lymphoplasma cell infiltration around the capsule increased more after treatment than they did in a control group. Capsular thickness, inner thinner collagen layer, and capsule wall collagen deposition decreased after shock wave treatment; only the inner thinner collagen layer and capsule wall collagen deposition changed significantly. The MRI findings for both scar thickness and water content were consistent with pathological biology findings.

Conclusion

This was the first pilot study and trial to treat capsular contractures using shock waves. We found that shock waves can cause changes in the structure or the composition of capsular contracture. We conclude that the treatment could decrease water content, loosen structure, decrease collagen deposition, and might alleviate scar formation from capsular contracture. We believe that the treatment could be a viable remedy for capsular contractures.

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Acknowledgments

This work was supported by grants from Kaohsiung Armed Force general Hospital, Taiwan (No. 101-17 and 102-10).

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Authors and Affiliations

  1. Department of Biomedical Engineering, I-Shou University, Kaohsiung, Taiwan

    Po Chou Chen & Shyh Ming Kuo

  2. Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan

    Jo Chi Jao & Shiou Wen Yang

  3. Department of Surgery, Kaohsiung Armed Force General Hospital, Kaohsiung, Taiwan

    Ching Wen Hsu

  4. Department of Surgery, Kaohsiung Armed Force General Hospital, No.2, Zhongzheng 1st Rd., Lingya District, Kaohsiung, 80284, Taiwan

    Yu Chiuan Wu

  5. National Kaohsiung University of Hospitality and Tourism, Kaohsiung, Taiwan

    Yu Chiuan Wu

  6. Yuh-Ing Junior College of Health Care and Management, Kaohsiung, Taiwan

    Yu Chiuan Wu

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  1. Po Chou Chen
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Correspondence to Yu Chiuan Wu.

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Chen, P.C., Kuo, S.M., Jao, J.C. et al. Noninvasive Shock Wave Treatment for Capsular Contractures After Breast Augmentation: A Rabbit Study. Aesth Plast Surg 40, 435–445 (2016). https://doi.org/10.1007/s00266-016-0643-8

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  • DOI: https://doi.org/10.1007/s00266-016-0643-8

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