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Diagnosis of osteosarcoma in a patient previously treated for Ewing sarcoma

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Abstract

Primary malignant bone tumors, whether Ewing sarcoma or osteosarcoma, are a rare type of tumor. The sequential occurrence of two bone sarcomas, Ewing sarcoma and high-grade osteosarcoma, in the same patient at two different locations is an exceptionally rare phenomenon. We present the case of a 13-year-old girl who presented with a high-grade osteoblastic osteosarcoma of the distal femur, 7 years after treatment for Ewing sarcoma of the left pelvis. She did not receive radiation therapy. Following the recent developing multidisciplinary therapy, long-term follow-up for monitoring latent treatment-related adverse effects may be necessary for survivors of primary malignant bone tumors.

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Acknowledgements

We thank Kenichi Wakasa for the pathological examinations and interpretations.

Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Department of Orthopedic Surgery, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-Machi, Abeno-Ku, Osaka, 545-8585, Japan

    Manabu Hoshi, Makoto Ieguchi & Hiroaki Nakamura

  2. Department of Pediatrics, Osaka City University Graduate School of Medicine, 1-4-3 Asahi-Machi, Abeno-Ku, Osaka, 545-8585, Japan

    Kazumi Yamato & Sadao Tokimasa

Authors
  1. Manabu Hoshi
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  2. Makoto Ieguchi
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  3. Kazumi Yamato
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  4. Sadao Tokimasa
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  5. Hiroaki Nakamura
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Correspondence to Manabu Hoshi.

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Hoshi, M., Ieguchi, M., Yamato, K. et al. Diagnosis of osteosarcoma in a patient previously treated for Ewing sarcoma. Skeletal Radiol 43, 1319–1324 (2014). https://doi.org/10.1007/s00256-014-1880-z

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  • DOI: https://doi.org/10.1007/s00256-014-1880-z

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