Abstract
The authors report an unusual case of radial mononeuropathy caused by epithelioid sarcoma and describe the anatomical 3-Tesla MR neurography and the functional diffusion tensor imaging findings of the case, which were subsequently confirmed on surgical excision and histopathology.
References
Wang LH, Weiss MD. Anatomical, clinical, and electrodiagnostic features of radial neuropathies. Phys Med Rehabil Clin N Am. 2013;24(1):33–47.
Rozen WM, Galloway S, Salinas C, Allen P, Schlicht S, Mann GB. Fasciitis ossificans with a radial neuropathy: a benign differential diagnosis for soft tissue sarcoma. J Clin Neurosci. 2007;14(4):391–4.
Enzinger FM. Epithelioid sarcoma. A sarcoma simulating a granuloma or a carcinoma. Cancer. 1970;26(5):1029–41.
Bos GD, Pritchard DJ, Reiman HM, Dobyns JH, Ilstrup DM, Landon GC. Epithelioid sarcoma. An analysis of fifty-one cases. J Bone Joint Surg Am. 1988;70(6):862–70.
Prat J, Woodruff JM, Marcove RC. Epithelioid sarcoma: an analysis of 22 cases indicating the prognostic significance of vascular invasion and regional lymph node metastasis. Cancer. 1978;41(4):1472–87.
Agarwal M, Shatma MC, Deol P, Mehta VS, Sarkar C. Epithelioid sarcoma of the sciatic nerve perineural sheath: a mimic of nerve sheath tumor. Pathol Oncol Res. 2002;8(2):148–50.
Harish S, Saifuddin A, Fajinmi M. Epithelioid sarcoma of the median nerve mimicking a peripheral nerve sheath tumour. Australas Radiol. 2007;51(1):71–4.
Faridian-Aragh N, Chalian M, Soldatos T, Thawait GK, Deune EG, Belzberg AJ, et al. High-resolution 3 T MR neurography of radial neuropathy. J Neuroradiol. 2011;38(5):265–74.
Halling AC, Wollan PC, Pritchard DJ, Vlasak R, Nascimento AG. Epithelioid sarcoma: a clinicopathologic review of 55 cases. Mayo Clin Proc. 1996;71(7):636–42.
Chase DR, Enzinger FM. Epithelioid sarcoma. Diagnosis, prognostic indicators, and treatment. Am J Surg Pathol. 1985;9(4):241–63.
Hornick JL, Dal Cin P, Fletcher CD. Loss of INI1 expression is characteristic of both conventional and proximal-type epithelioid sarcoma. Am J Surg Pathol. 2009;33(4):542–50.
Hanna SL, Kaste S, Jenkins JJ, Hewan-Lowe K, Spence JV, Gupta M, et al. Epithelioid sarcoma: clinical, MR imaging and pathologic findings. Skeletal Radiol. 2002;31(7):400–12.
Chhabra A, Williams EH, Wang KC, Dellon AL, Carrino JA. MR neurography of neuromas related to nerve injury and entrapment with surgical correlation. AJNR Am J Neuroradiol. 2010;31(8):1363–8.
Chhabra A, Thakkar RS, Andreisek G, Chalian M, Belzberg AJ, Blakeley J, et al. Anatomic MR imaging and functional diffusion tensor imaging of peripheral nerve tumors and tumorlike conditions. AJNR Am J Neuroradiol. 2012. doi:10.3174/ajnr.A3316
Scheithauer BW, Amrami KK, Folpe AL, Silva AI, Edgar MA, Woodruff JM, et al. Synovial sarcoma of nerve. Hum Pathol. 2011;42(4):568–77.
Thawait SK, Chaudhry V, Thawait GK, Wang KC, Belzberg A, Carrino JA, et al. High-resolution MR neurography of diffuse peripheral nerve lesions. AJNR Am J Neuroradiol. 2011;32(8):1365–72.
Randall RL, Dailey A, Albritton KH, Olson PR, Coffin CM. Case reports: fibrosarcoma metastatic to the sciatic nerve. Clin Orthop Relat Res. 2005;(437):242–6.
Guggenberger R, Markovic D, Eppenberger P, Chhabra A, Schiller A, Nanz D, et al. Assessment of median nerve with MR neurography by using diffusion-tensor imaging: normative and pathologic diffusion values. Radiology. 2012;265(1):194–203.
Tagliafico A, Calabrese M, Puntoni M, Pace D, Baio G, Neumaier CE, et al. Brachial plexus MR imaging: accuracy and reproducibility of DTI-derived measurements and fibre tractography at 3.0-T. Eur Radiol. 2011;21(8):1764–71.
Vargas MI, Viallon M, Nguyen D, Delavelle J, Becker M. Diffusion tensor imaging (DTI) and tractography of the brachial plexus: feasibility and initial experience in neoplastic conditions. Neuroradiology. 2010;52(3):237–245.
Hodaie M, Chen DQ, Quan J, Laperriere N. Tractography delineates microstructural changes in the trigeminal nerve after focal radiosurgery for trigeminal neuralgia. PLoS One. 2012;7(3):e32745.
Conflicts of interest
Vibhor Wadhwa: The author reports no conflicts of interest.
Safia N. Salaria: The author reports no conflicts of interest.
Rashmi S. Thakkar: The author reports no conflicts of interest.
Dr. Chhabra has received patient research grants from Siemens, Interga Life Sciences and GE-AUR. He also serves as MSK CAD consultant with Siemens.
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Wadhwa, V., Salaria, S.N., Thakkar, R.S. et al. Epithelioid sarcoma presenting as radial mononeuropathy: anatomical, magnetic resonance neurography and diffusion tensor imaging appearances. Skeletal Radiol 42, 853–858 (2013). https://doi.org/10.1007/s00256-013-1591-x
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DOI: https://doi.org/10.1007/s00256-013-1591-x