Skeletal Radiology

, Volume 39, Issue 11, pp 1109–1116

Measurements of bone mineral density in the lumbar spine and proximal femur using lunar prodigy and the new pencil-beam dual-energy X-ray absorptiometry

Authors

  • Dongil Choi
    • Clinical Trial Center, Clinical Research Institute, Samsung Medical CenterSungkyunkwan University School of Medicine
    • Department of Radiology, Samsung Medical CenterSungkyunkwan University School of Medicine
    • Department of Nuclear Medicine, College of MedicineKyung Hee University
  • Chung Soo Han
    • Department of Orthopedic Surgery, College of MedicineKyung Hee University
  • Seonwoo Kim
    • Clinical Trial Center, Clinical Research Institute, Samsung Medical CenterSungkyunkwan University School of Medicine
    • Biostatistics Unit, Samsung Biomedical Research InstituteSamsung Medical Center
  • Hae Sook Bok
    • Clinical Trial Center, Clinical Research Institute, Samsung Medical CenterSungkyunkwan University School of Medicine
  • Wooseong Huh
    • Clinical Trial Center, Clinical Research Institute, Samsung Medical CenterSungkyunkwan University School of Medicine
    • Division of Nephrology, Samsung Medical CenterSungkyunkwan University School of Medicine
  • Jae-Wook Ko
    • Clinical Trial Center, Clinical Research Institute, Samsung Medical CenterSungkyunkwan University School of Medicine
    • Division of Clinical Pharmacology, Clinical Research Institute, Samsung Medical CenterSungkyunkwan University School of Medicine
  • Sung Hwa Hong
    • Clinical Trial Center, Clinical Research Institute, Samsung Medical CenterSungkyunkwan University School of Medicine
    • Department of Otorhinolaryngology-Head and Neck Surgery, Samsung Medical CenterSungkyunkwan University School of Medicine
Scientific Article

DOI: 10.1007/s00256-009-0828-1

Cite this article as:
Choi, D., Kim, D., Han, C.S. et al. Skeletal Radiol (2010) 39: 1109. doi:10.1007/s00256-009-0828-1

Abstract

Objective

We evaluated the correlation of the absolute bone mineral density (BMD) values of the lumbar spine and standard sites of the proximal femur obtained from a Lunar Prodigy and the newly developed pencil-beam dual-energy X-ray absorptiometry (Dexxum).

Materials and methods

Between June 2008 and December 2008, 79 Korean volunteers were enrolled. Measurements were obtained on the same day using both densitometers. The absolute BMD values (g/cm2) from the two densitometers were evaluated using Pearson’s correlation analysis with Bonferroni’s correction for the three clinically important sites. In order to evaluate precision, we performed duplicate Dexxum measurements, and calculated the within-subject coefficient of variation (WSCV).

Results

The Pearson’s correlation coefficient (r) of BMD values for the total proximal femur, femoral neck, and lumbar spine by the two densitometers were 0.926, 0.948, and 0.955 respectively, and the null hypotheses of r = 0.8 were all rejected (p < 0.001 by one-sided Z-test with Fisher’s z-transformation for each site). The T-scores (r ≧ 0.842) and Z-scores (r ≧ 0.709) also showed strong positive correlations. The duplicate BMD values of Dexxum showed a high level of precision (WSCV ≦ 4.27%).

Conclusion

Dexxum measurements of BMD, T-scores, and Z-scores showed a strong linear correlation with those measured on Lunar Prodigy.

Keywords

Bone mineral density Pencil-beam dual-energy X-ray absorptiometry T-scores Z-scores Precision

Copyright information

© ISS 2009