Skip to main content
Log in

Xenx (Xenolith): preliminary considerations of a new “all-in-one” ureteral guidewire and anti-repulsion device

  • Original Paper
  • Published:
Urolithiasis Aims and scope Submit manuscript

Abstract

A new anti-retropulsion device for the endoscopic treatment of ureteral stones was evaluated for safety and potential efficacy. The Xenx™ (Rocamed, Monaco-Montecarlo) is an anti-retropulsion device that operates as a normal hydrophilic guidewire when “closed” and as a nitinol ureteral mesh when “open”. We performed semirigid ureterorenoscopy and Ho:YAG Laser lithotripsy in 15 patients, with a single ureteral stone. For each procedure, the papilla was negotiated with the Xenx™, the radiopaque markers were positioned over the stone via direct visualization and the device was opened under fluoroscopic control. The ureteroscope was then retracted and reinserted beside the Xenx™. At the end of the procedure, the Xenx™ was closed, and a ureteral catheter was coaxially placed and left for 24–48 h post-operation. We evaluated device positioning success with respect to pushability, ease of deployment, full expansion and fitting with the ureteral walls, kink resistance and stone retention capabilities during lithotripsy and device retrieval. Operative time, post-operative complications (Clavien-Dindo scale), ultrasound kidney stone-free rate and the hydronephrosis grade, were also recorded. At 4 weeks post-operation, the stone-free rate was assessed via non-contrast computed tomography with 1-mm slices. All procedures were successfully accomplished without complications according to the Clavien-Dindo scale. In all the cases, Xenx™ was inserted successfully past the stone and opened over it. In 4/15 cases (27 %) some difficulties in pushability and kink resistance were recorded. In no case stone fragment basketing was performed. The median operative time was 24 min. At hospital discharge, 14/15 patients (93 %) were kidney stone-free. At 4 weeks, the NCCT stone-free rate was 100 %. This study demonstrated that the Xenx™ is safe and effective in terms of the stone-free rate, complications and operating time. Moreover, use of the Xenx™ allows the use of a basket or guide wire to be avoided.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Wosnitzer M, Xavier K, Gupta M (2009) Novel use of a ureteroscopic stone entrapment device to prevent antegrade stone migration during percutaneous nephrolithotomy. J Endourol 23:203–208

    Article  PubMed  Google Scholar 

  2. Pedro RN, Hendlin K, Weiland D et al (2007) In vitro evaluation of ureteral perforation forces. Urology 70:592–594

    Article  PubMed  Google Scholar 

  3. Dretler SP (2001) The stone cone: a new generation of basketry. J Urol 165:1593–1596

    Article  CAS  PubMed  Google Scholar 

  4. Finley DS, Petersen J, Abdelshehid C et al (2005) Effect of holmium:YAG laser pulse width on lithotripsy retropulsion in vitro. J Endourol 19:1041–1044

    Article  PubMed  Google Scholar 

  5. Lee H, Ryan RT, Teichman JM et al (2003) Stone retropulsion during holmium:YAG lithotripsy. J Urol 169:881–885

    Article  PubMed  Google Scholar 

  6. Marguet CG, Sung JC, Springhart WP et al (2005) In vitro comparison of stone retropulsion and fragmentation of the frequency doubled, double pulse nd:YAG laser and the holmium:YAG laser. J Urol 173:1797–1800

    Article  PubMed  Google Scholar 

  7. Sarkissian C, Paz A, Zigman O, Webster K, Tamir I, Monga M (2012) Safety and efficacy of a novel ureteral occlusion device. Urology 80:327

    Article  Google Scholar 

  8. Macchione N, Sanguedolce F, Stephan H, Longo F, Karchrilas S, Masood J, Bucholz N, Montanari E (2013) A novel stone management device during endolithotripsy for ureteral stones: first multi-institutional experience. J Endourol 27:A470

    Article  Google Scholar 

  9. Macchione N, Sanguedolce F, Stephan H, Longo F, Karchrilas S, Masood J, Bucholz N, Montanari E (2014) Xenx (Xenolith), a new anti-repulsion device in the treatment of ureteral stones: a multicenter European study. Eur Urol Suppl 13:eV6

    Article  Google Scholar 

  10. Macchione N, Longo F, Zanetti G, Trinchieri A, Montanari E (2013) Xenx, a new device to prevent stone and fragments migration during the endoscopic laser lithotripsy: experience in a single center. Eur Urol Suppl 12:47

    Article  Google Scholar 

  11. Turney BW, Reynard JM, Noble JG et al (2011) Trends in urological stone disease. BJU Int 109:1082–1087

    Article  PubMed  Google Scholar 

  12. Elashry OM, Elgamasy AK, Sabaa MA et al (2008) Ureteroscopic management of lower ureteric calculi: a 15-year single-centre experience. BJU Int 102:1010–1017

    Article  PubMed  Google Scholar 

  13. Sea J, Jonat LM, Chew BH et al (2012) Optimal power settings for holmium:YAG lithotripsy. J Urol 187:914–919

    Article  PubMed  Google Scholar 

  14. Chew B, Poh B, Jonat L et al (2011) Anti-retropulsion devices increase stone fragmentation efficiency with holmium:YAG laser lithotripsy. Urology 78:S376

    Article  Google Scholar 

  15. Lee HJ, Box GN, Abraham JB et al (2008) In vitro evaluation of nitinol urological retrieval coil and ureteral occlusion device: retropulsion and holmium laser fragmentation efficiency. J Urol 180:969–973

    Article  PubMed  Google Scholar 

  16. Elashry OM, Tawfik AM (2012) Preventing stone retropulsion during intracorporeal lithotripsy. Nat Rev Urol 9:691–698

    Article  PubMed  Google Scholar 

  17. Olbert PJ, Keil C, Weber J et al (2010) Efficacy and safety of the Accordion stone-trapping device: in vitro results from an artificial ureterolithotripsy model. Urol Res 38:41–46

    Article  PubMed  Google Scholar 

  18. Abdelsayed M, Onal E, Wax SH (1977) Avulsion of the ureter caused by stone basket manipulation. J Urol 118:868–870

    CAS  PubMed  Google Scholar 

  19. Durano AC, Hanosh JJ (1988) A new alternative treatment for entrapped stone basket in the distal ureter. J Urol 139:116–117

    PubMed  Google Scholar 

  20. Ursiny M, Eisner BH (2013) Cost-effectiveness of anti-retropulsion devices for ureteroscopic lithotripsy. J Urol 189:1762–1766

    Article  PubMed  Google Scholar 

  21. Ahmed M, Pedro RN, Kieley S et al (2009) Systematic evaluation of ureteral occlusion devices: insertion, deployment, stone migration, and extraction. Urology 73:976–980

    Article  PubMed  Google Scholar 

Download references

Conflict of interest

No competing financial interests exist.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Fabrizio Longo.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Montanari, E., Longo, F., Macchione, N. et al. Xenx (Xenolith): preliminary considerations of a new “all-in-one” ureteral guidewire and anti-repulsion device. Urolithiasis 43, 177–182 (2015). https://doi.org/10.1007/s00240-014-0740-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00240-014-0740-6

Keywords

Navigation