Abstract
Since Hick’s original description, many subsequent studies have confirmed the logarithmic relationship that exists between response time and the number of alternatives (NA) for a choice response. In the present study a novel paradigm was used to quantify saccade response time as a function of NA. Normal subjects were required to make a saccade to the remembered location of a visual target whose color was specified by a centrally located cue. The paradigm thus required a stimulus-response transformation similar to that used by Hick. The results show that, when such a transformation was required, a logarithmic relationship was found for saccadic response time. The use of a color-to-location paradigm to study saccade choice response time produced an unexpected additional result that may provide insight into the neural organization of the saccadic system. When the number of alternative choice responses was large (4 or 8), subjects frequently made a two-saccade response instead of a single saccade to the correct location. The first movement in such a sequence was in the correct direction, but was hypometric. A second movement then followed which moved the eyes onto the correct location. These results suggest dynamic dissociations in the mechanisms underlying the triggering of saccades and the specification of their metrics.
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References
Anderson RW, Keller EL, Gandhi NJ, Das S (1998) Two-dimensional saccade-related population activity in superior colliculus in monkey. J Neurophysiol 80:798–817
Basso MA, Wurtz RH (1998) Modulation of neuronal activity in superior colliculus by changes in target probability. J Neurosci 18:7519–7534
Becker W, Juergens R (1979) An analysis of the saccadic system by means of double step stimuli. Vision Res 19:967–983
Carpenter RH, Williams ML (1995) Neural computation of log likelihood in control of saccadic eye movements. Nature 377:59–62
Christie LS, Luce RD (1956) Decision structure and time relations in simple choice behavior. Bull Math Biophys 18:89–112
Crane HD, Steele CM (1985) Generation-V dual-Purkinje-image eyetracker. Applied Optics 24:527–537
Deubel H, Bridgeman B (1995) Fourth Purkinje image signals reveal eye-lens deviations and retinal image distortions during saccades. Vision Res 35:529–538
Findlay JM, Walker R (1999) A model of saccade generation based on parallel processing and competitive inhibition. Behav Brain Sci 22:661–674
Fitts PM, Posner MI (1967) Human performance. Brooke/Cole Publishing Co., Belmont, CA
Fuchs AF, Robinson FR, Straube A (1993) Role of the caudal fastigial nucleus in saccade generation. I Neuronal discharge patterns. J Neurophysiol 70:1723–1740
Hallett PE, Adams B (1980) The predictability of saccadic latency in a novel voluntary oculomotor task. Vision Res 20:329–339
Heywood S, Churcher J (1980) Structure of the visual array and saccadic latency: implications for oculomotor control. Q J Exp Psychol 32:335–341
Hick WE (1952) On the rate of gain of information. Q J Exp Psychol 4:11–26
Hyman R (1953) Stimulus information as a determinant of reaction time. J Exp Psychol 45:188–196
Keller EL, Edelman JA (1994) Use of interrupted saccade paradigm to study spatial and temporal dynamics of saccadic burst cells in superior colliculus in monkey. J Neurophysiol 72:2754–2770
Keller EL, Gandhi NJ, Shieh JM (1996) Endpoint accuracy in saccades interrupted by stimulation in the omnipause region in monkey. Vis Neurosci 13:1059–1067
Kimmig H, Haussmann K, Mergner T, Lucking CH (2002) What is pathological with gaze shift fragmentation in Parkinson’s disease? J Neurol 249:683–692
Kveraga K, Boucher L, Hughes HC (2002) Saccades operate in violation of Hick’s law. Exp Brain Res 146:307–314
Laming DRJ (1966) A new interpretation of the relation between choice-reaction time and the number of equiprobable. Br J Math Stat Psychol 19:139–149
Laming DRJ (1968) Information theory of choice-reaction times. Academic Press, New York
Leonard JA (1959) Tactual choice reactions: I. Q J Exp Psychol 11:76–83
Luce RD (1986) Response times: their role in inferring elementary mental organization. Oxford University Press, New York
Martinez-Conde S, Macknik SL, Hubel DH (2004) The role of fixational eye movements in visual perception. Nat Rev Neurosci 5:229–240
May PJ, Hartwich-Young R, Nelson J, Sparks DL, Porter JD (1990) Cerebellotectal pathways in the macaque: implications for collicular generation of saccades. Neuroscience 36:305–324
McPeek RM, Skavenski AA, Nakayama K (2000) Concurrent processing of saccades in visual search. Vision Res 40:2499–2516
Morin RE, Forrin B (1962) Mixing of two types of S-R associations in a choice reaction time task. J Exp Psychol 64:137–141
Morin RE, Konick A, Troxell N, McPherson S (1965) Information and reaction time for naming responses. J Exp Psychol 70:314
Munoz DP, Wurtz RH (1995) Saccade-related activity in monkey superior colliculus. I. Characteristics of burst and buildup cells. J Neurophysiol 73:2313–2333
Munoz DP, Waitzman DM, Wurtz RH (1996) Activity of neurons in monkey superior colliculus during interrupted saccades. J Neurophysiol 75:2562–2580
Noda H, Sugita S, Ikeda Y (1990) Afferent and efferent connections of the oculomotor region of the fastigial nucleus in the macaque monkey. J Comp Neurol 302:330–348
Oldfield RC, Wingfield A (1965) Response latencies in naming objects. Q J Exp Psychol 17:273–281
Pachella RG (1974) The interpretation of reaction time in information processing research. In: Kantowitz BH (ed) Human information processing: tutorials in performance and cognition. Lawrence Erlbaum Associates, Hillsdale, NJ, pp 41–82
Quaia C, Lefevre P, Optican LM (1999) Model of the control of saccades by superior colliculus and cerebellum. J Neurophysiol 82:999–1018
Reddi BA, Carpenter RH (2000) The influence of urgency on decision time. Nat Neurosci 3:827–830
Reddi BA, Asrress KN, Carpenter RH (2003) Accuracy, information, and response time in a saccadic decision task. J Neurophysiol 90:3538–3546
Rucker JC, Shapiro BE, Han YH, Kumar AN, Garbutt S, Keller EL, Leigh RJ (2004) Neuro-ophthalmology of late-onset Tay-Sachs disease (LOTS). Neurology, in press
Schall JD (2001) Neural basis of deciding, choosing, and acting. Nature Rev Neurosci 2:33–42
Scudder CA, Kaneko CS, Fuchs AF (2002) The brainstem burst generator for saccadic eye movements: a modern synthesis. Exp Brain Res 142:439–462
Stanford TR, Sparks DL (1994) Systematic errors for saccades to remembered targets: evidence for a dissociation between saccade metrics and activity in the superior colliculus. Vision Res 34:93–106
Teichner WH, Krebs MJ (1974) Laws of visual choice reaction time. Psychol Rev 81:75–98
Usher M, Olami Z, McClelland JL (2002) Hick’s law in a stochastic race model with speed-accuracy tradeoff. J Math Psychol 46:704–715
Van Gisbergen JA, Robinson DA, Gielen S (1981) A quantitative analysis of generation of saccadic eye movements by burst neurons. J Neurophysiol 45:417–442
Welford AT (1960) The measurement of sensory-motor performance: survey and reappraisal of twelve years’ progress. Ergonomics 3:189–230
Welford AT (1968) Fundamentals of skill. Methuen, London
Wyszecki G, Stiles WS (1982) Color science: concepts and methods, quantitative data and formulae. John Wiley & Sons, Inc, New York
Yoshida K, Iwamoto Y, Chimoto S, Shimazu H (1999) Saccade-related inhibitory input to pontine omnipause neurons: An intracellular study in alert cats. J Neurophysiol 82:1198–1208
Acknowledgements
We thank Dr. Rob McPeek for his insightful comments. This work was supported by the Visiting Scholar Program of The Smith-Kettlewell Eye Research Institute, a grant (M103KV010021-03K2201-02120) from Brain Research Center of the 21st Century Frontier Research Program funded by the Ministry of Science and Technology of Republic of Korea (K.M.L.), and NIH Grant EY08060 (E.L.K.).
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Lee, KM., Keller, E.L. & Heinen, S.J. Properties of saccades generated as a choice response. Exp Brain Res 162, 278–286 (2005). https://doi.org/10.1007/s00221-004-2186-5
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DOI: https://doi.org/10.1007/s00221-004-2186-5