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Well characterized antihistamine 4 receptor antibodies contribute to current knowledge of the expression and biology of the human and murine histamine 4 receptor

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References

  • Bäumer W, Wendorff S, Gutzmer R, Werfel T, Dijkstra D, Chazot P, Stark H, Kietzmann M (2008) Histamine H4 receptors modulate dendritic cell migration through skin—immunomodulatory role of histamine. Allergy 63:1387–1394

    Article  PubMed  Google Scholar 

  • Beermann S, Seifert R, Neumann D (2012) Commercially available antibodies against human and murine histamine H(4)-receptor lack specificity. Naunyn Schmiedebergs Arch Pharmacol 385(2):125–135

    Article  PubMed  CAS  Google Scholar 

  • Connelly WM, Shenton FC, Lethbridge N, Leurs R, Waldvogel HJ, Faull RL, Lees G, Chazot PL (2009) The histamine H4 receptor is functionally expressed on neurons in the mammalian CNS. Br J Pharmacol 157:55–63, May

    Article  PubMed  CAS  Google Scholar 

  • Dijkstra D, Stark H, Chazot PL, Shenton FC, Leurs R, Werfel T, Gutzmer R (2008) Human inflammatory dendritic epidermal cells express a functional histamine H4 receptor. J Invest Dermatol 128:1696–1703

    Article  PubMed  CAS  Google Scholar 

  • Gschwandtner M, Rossbach K, Dijkstra D, Bäumer W, Kietzmann M, Stark H, Werfel T, Gutzmer R (2010) Murine and human Langerhans cells express a functional histamine H4 receptor: modulation of cell migration and function. Allergy 65:840–849

    Article  PubMed  CAS  Google Scholar 

  • Lethbridge NL, Chazot PL (2010) Immunological identification of the mouse H4 histamine receptor on spinal cord motor neurons using a novel anti-mouse H4R antibody. Inflamm Res 59(Suppl 2):S197–S198

    Article  PubMed  CAS  Google Scholar 

  • van Rijn RM, Chazot PL, Shenton FC, Sansuk K, Bakker RA, Leurs R (2006) Oligomerization of recombinant and endogenously expressed human histamine H4 receptors. Mol Pharmacol 70:604–615

    Article  PubMed  Google Scholar 

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Correspondence to Wolfgang Bäumer.

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Gutzmer, R., Werfel, T., Bäumer, W. et al. Well characterized antihistamine 4 receptor antibodies contribute to current knowledge of the expression and biology of the human and murine histamine 4 receptor. Naunyn-Schmiedeberg's Arch Pharmacol 385, 853–854 (2012). https://doi.org/10.1007/s00210-012-0744-0

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  • DOI: https://doi.org/10.1007/s00210-012-0744-0

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