Abstract
Summary
This 1-year cohort study of nursing home residents revealed that historical fractures of upper limbs or nonhip lower limbs were associated with hip fracture (hazard ratio = 2.14), independent of activities of daily living (ADL), mobility, dementia, weight, and type of nursing home. Prior nonhip fractures are useful for predicting of hip fracture in institutional settings.
Introduction
The aim of this study was to evaluate the utility of fracture history for the prediction of hip fracture in nursing home residents.
Methods
This was a cohort study with a 1-year follow-up. Subjects were 8,905 residents of nursing homes in Niigata, Japan (mean age, 84.3 years). Fracture histories were obtained from nursing home medical records. ADL levels were assessed by caregivers. Hip fracture diagnosis was based on hospital medical records.
Results
Subjects had fracture histories of upper limbs (5.0%), hip (14.0%), and nonhip lower limbs (4.6%). Among historical single fractures, only prior nonhip lower limbs significantly predicted subsequent fracture (adjusted hazard ratio, 2.43; 95% confidence interval (CI), 1.30–4.57). The stepwise method selected the best model, in which a combined historical fracture at upper limbs or nonhip lower limbs (adjusted hazard ratio, 2.14; 95% CI, 1.30–3.52), dependence, ADL levels, mobility, dementia, weight, and type of nursing home independently predicted subsequent hip fracture.
Conclusions
A fracture history at upper or nonhip lower limbs, in combination with other known risk factors, is useful for the prediction of future hip fracture in institutional settings.
Similar content being viewed by others
References
Magaziner J, Fredman L, Hawkes W et al (2003) Changes in functional status attributable to hip fracture: a comparison of hip fracture patients to community-dwelling aged. Am J Epidemiol 157:1023–1031
Ota T, Harada A, Tokuda H (2002) Cost-effectiveness of hip fracture in Japan. Jpn J Geriat 39:483–488 (in Japanese)
Ishikawa M, Nakamura K, Tamura T et al (2006) Ethnic differences between Asians and Caucasians in the incidence of osteoporotic fractures: a review. Acta Med Biol 54:63–66
Morita Y, Endo N, Iga T et al (2002) The incidence of cervical and trochanteric fractures of the proximal femur in 1999 in Niigata Prefecture, Japan. J Bone Miner Metab 20:311–318
Butler M, Norton R, Lee-Joe T et al (1996) The risks of hip fracture in older people from private homes and institutions. Age Ageing 25:381–385
Sugarman JR, Connell FA, Hansen A et al (2002) Hip fracture incidence in nursing home residents and community-dwelling older people, Washington State, 1993–1995. J Am Geriatr Soc 50:1638–1643
Nakamura K, Oyama M, Takahashi S, et al. (in press) Fracture incidence in nursing homes in Japan. Osteoporos Int
Girman CJ, Chandler JM, Zimmerman SI et al (2002) Prediction of fracture in nursing home residents. J Am Geriatr Soc 50:1341–1347
Walter LC, Lui LY, Eng C et al (2003) Risk of hip fracture in disabled community-living older adults. J Am Geriatr Soc 51:50–55
Greenspan SL, Myers ER, Kiel DP et al (1998) Fall direction, bone mineral density, and function: risk factors for hip fracture in frail nursing home elderly. Am J Med 104:539–545
Chandler JM, Zimmerman SI, Girman CJ et al (2000) Low bone mineral density and risk of fracture in white female nursing home residents. JAMA 284:972–977
Sambrook PN, Cameron ID, Chen JS et al (2007) Influence of fall related factors and bone strength on fracture risk in the frail elderly. Osteoporos Int 18:603–610
Klotzbuecher CM, Ross PD, Landsman PB et al (2000) Patients with prior fractures have an increased risk of future fractures: a summary of the literature and statistical synthesis. J Bone Miner Res 15:721–739
Kanis JA, Johnell O, De Laet C et al (2004) A meta-analysis of previous fracture and subsequent fracture risk. Bone 35:375–382
Colón-Emeric CS, Biggs DP, Schenck AP et al (2003) Risk factors for hip fracture in skilled nursing facilities: who should be evaluated? Osteoporos Int 14:484–489
Lyles KW, Schenck AP, Colón-Emeric CS (2008) Hip and other osteoporotic fractures increase the risk of subsequent fractures in nursing home residents. Osteoporos Int 19:1225–1233
Mahoney FI, Barthel DW (1965) Functional evaluation: the Barthel Index. Md State Med J 14:61–65
Takigawa Y (1994) Criteria for independence of demented elderly people (authors' translation). Koshu-Eisei (J Public Health Pract) 58:73–75 (in Japanese)
Nakamura K, Takahashi S, Oyama M et al (2009) Incidence and risk factors associated with hip fracture in institutionalised elderly people in Japan. Age Ageing 38:478–482
Schousboe JT, Fink HA, Taylor BC et al (2005) Association between self-reported prior wrist fractures and risk of subsequent hip and radiographic vertebral fractures in older women: a prospective study. J Bone Miner Res 20:100–106
Hodsman AB, Leslie WD, Tsang JF et al (2008) 10-year probability of recurrent fractures following wrist and other osteoporotic fractures in a large clinical cohort: an analysis from the Manitoba Bone Density Program. Arch Intern Med 168:2261–2267
Dargent-Molina P, Poitiers F, Bréart G, EPIDOS Group (2000) In elderly women weight is the best predictor of a very low bone mineral density: evidence from the EPIDOS study. Osteoporos Int 11:881–888
Nakamura K, Saito T, Nishiwaki T et al (2006) Correlations between bone mineral density and demographic, lifestyle, and biochemical variables in community-dwelling Japanese women 69 years of age and over. Osteoporos Int 17:1202–1207
Schousboe JT, Fink HA, Lui LY et al (2006) Association between prior non-spine non-hip fractures or prevalent radiographic vertebral deformities known to be at least 10 years old and incident hip fracture. J Bone Miner Res 21:1557–1564
Johnell O, Kanis JA, Odén A et al (2004) Fracture risk following an osteoporotic fracture. Osteoporos Int 15:175–179
Acknowledgments
We wish to thank the Niigata Council of Institutions for the Elderly for their assistance in data collection. We also thank Ms. A. Kagoshima for help with data analysis. This study was supported in part by a grant from the Chiyoda Mutual Life Foundation, 2006.
Conflicts of interest
None.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Nakamura, K., Takahashi, S., Oyama, M. et al. Prior nonhip limb fracture predicts subsequent hip fracture in institutionalized elderly people. Osteoporos Int 21, 1411–1416 (2010). https://doi.org/10.1007/s00198-009-1081-0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00198-009-1081-0