Skip to main content

Advertisement

SpringerLink
Log in

Correlation of bladder wall thickness and treatment success in types of urinary incontinence

  • Original Article
  • Published:
International Urogynecology Journal Aims and scope Submit manuscript

Abstract

Introduction and hypothesis

The aim of the study was to investigate the correlation between mean bladder wall thickness (BWT) and treatment success in patients diagnosed with urinary incontinence, based on urodynamic test results.

Methods

In this prospective study, patient urinary incontinence type was identified using urodynamic tests. Patients (N = 125) were categorized into three groups: urodynamic stress incontinence (SUI), detrusor over-activity (DO) and mixed urinary incontinence. Measurements from the bladder dome, anterior wall and trigone were averaged to calculate BWT. Student’s t test and Mann–Whitney U test were used to compare pre-treatment BWT. Receiver operating characteristic (ROC) curve analysis was used to determine optimal cut-off values for BWT to predict treatment success.

Results

Mean pre-treatment BWT significantly differed between success and non-success groups for each urinary incontinence type (p value for the SUI, DO and MUI groups was 0.043, 0.001 and 0.002 respectively). Using ROC curves to anticipate the treatment success, a threshold was calculated for mean pre-treatment BWT; 5.05 mm for SUI (sensitivity 74 %, specificity 66 %, positive predictive value [PPV] 85 %, negative predictive value [NPV] 50 %), 4.98 mm for DO (sensitivity 73 %, specificity 92 %, PPV 95 %, NPV 63 %) and 5.31 mm for mixed type (sensitivity 88 %, specificity 73 %, PPV 79 %, NPV 85 %).

Conclusions

The study results suggest a significant relationship between the pre-treatment BWT and the success of urinary incontinence treatment. The mean BWT may be used as a benchmark in assessing the responsiveness to treatment of urinary incontinence types.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

Abbreviations

BWT:

Bladder wall thickness

SUI:

Stress urinary incontinence

MUI:

Mixed urinary incontinence

DO:

Detrusor overactivity

PPV:

Positive predictive value

NPV:

Negative predictive value

ICS:

International Continence Society

BMI:

Body mass index

References

  1. Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U, et al. The standardisation of terminology of lower urinary tract function: report from the Standardisation Sub-committee of the International Continence Society, vol 21. Neurourol Urodyn 21(2):167–178

  2. Buckley BS, Lapitan MCM. Prevalence of urinary incontinence in men, women, and children—current evidence: findings of the fourth international consultation on incontinence. Urology. 2010;76(2):265–70.

    Article  PubMed  Google Scholar 

  3. Markland AD, Richter HE, Fwu C-W, Eggers P, Kusek JW. Prevalence and trends of urinary incontinence in adults in the United States, 2001 to 2008. J Urol. 2011;186(2):589–93.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Khullar V, Salvatore S, Cardozo L, Bourne TH, Abbott D, Kelleher C. A novel technique for measuring bladder wall thickness in women using transvaginal ultrasound. Ultrasound Obstet Gynecol. 1994;4(3):220–3. doi:10.1046/j.1469-0705.1994.04030220.x.

    Article  CAS  PubMed  Google Scholar 

  5. Serati M, Salvatore S, Cattoni E, Soligo M, Cromi A, Ghezzi F. Ultrasound measurement of bladder wall thickness in different forms of detrusor overactivity. Int Urogynecol J. 2010;21(11):1405–11.

    Article  PubMed  Google Scholar 

  6. Robinson D, Anders K, Cardozo L, Bidmead J, Toozs‐Hobson P, Khullar V. Can ultrasound replace ambulatory urodynamics when investigating women with irritative urinary symptoms? BJOG. 2002;109(2):145–8.

    Article  PubMed  Google Scholar 

  7. Panayi DC, Tekkis P, Fernando R, Hendricken C, Khullar V. Ultrasound measurement of bladder wall thickness is associated with the overactive bladder syndrome. Neurourol Urodyn. 2010;29(7):1295–8. doi:10.1002/nau.20871.

    Article  CAS  PubMed  Google Scholar 

  8. Uebersax JS, Wyman JF, Shumaker SA, McClish DK. Short forms to assess life quality and symptom distress for urinary incontinence in women: the incontinence impact questionnaire and the urogenital distress inventory. Neurourol Urodyn. 1995;14(2):131–9.

    Article  CAS  PubMed  Google Scholar 

  9. Haylen B. Residual urine volumes in a normal female population: application of transvaginal ultrasound. Br J Urol. 1989;64(4):347–9.

    Article  CAS  PubMed  Google Scholar 

  10. Haylen BT, De Ridder D, Freeman RM, Swift SE, Berghmans B, Lee J, et al. An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction. Int Urogynecol J. 2010;21(1):5–26.

    Article  PubMed  Google Scholar 

  11. Elbadawi A, Yalla S, Resnick N. Structural basis of geriatric voiding dysfunction. IV Bladder outlet obstruction. J Urol. 1993;150(5 Pt 2):1681–95.

    CAS  PubMed  Google Scholar 

  12. Khullar V, Cardozo L, Salvatore S, Hill S. Ultrasound: a noninvasive screening test for detrusor instability. BJOG. 1996;103(9):904–8.

    Article  CAS  Google Scholar 

  13. Yang J-M, Huang W-C. Bladder wall thickness on ultrasonographic cystourethrography affecting factors and their implications. J Ultrasound Med. 2003;22(8):777–82.

    Article  PubMed  Google Scholar 

  14. Arrighi N, Bodei S, Zani D, Simeone C, Cunico S, Spano P, et al. Acetylcholine induces human detrusor muscle cell proliferation: molecular and pharmacological characterization. Urologia. 2011;79(2):102–8.

    Article  Google Scholar 

  15. Wang L, Han L, Li H. Etiological study of pelvic organ prolapse and stress urinary incontinence with collagen status and metabolism. Zhonghua Yi Xue Za Zhi. 2013;93(7):500–3.

    CAS  PubMed  Google Scholar 

  16. Han L, Wang L, Wang Q, Li H, Zang H. Association between pelvic organ prolapse and stress urinary incontinence with collagen. Exp Ther Med. 2014;7(5):1337–41.

    PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgements

None.

Funding

No.

Author information

Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Dr Zekai Tahir Burak Woman’s Health Research and Education Hospital, Ankara, Turkey

    Burak Akselim, Melike Doğanay, Nilay Özcan & Sabri Cavkaytar

  2. Departments of Physical and Rehabilitation Medicine, Ankara Physical Medicine and Rehabilitation Training and Research Hospital, Ankara, Turkey

    Sinem Akselim

Authors
  1. Burak Akselim
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Melike Doğanay
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Nilay Özcan
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Sinem Akselim
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Sabri Cavkaytar
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Burak Akselim.

Ethics declarations

Conflicts of interest

The authors declare that they have no conflicts of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Akselim, B., Doğanay, M., Özcan, N. et al. Correlation of bladder wall thickness and treatment success in types of urinary incontinence. Int Urogynecol J 28, 417–422 (2017). https://doi.org/10.1007/s00192-016-3127-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00192-016-3127-0

Keywords

Search

Navigation