Abstract
Introduction and hypothesis
It has been claimed that post-void residual urine (PVR) below 150 ml rules out voiding dysfunction in women with stress urinary incontinence (SUI) and provides license to perform sling surgery. The cut-off of 150 ml seems arbitrary, not evidence-based, and so we sought to investigate the ability of PVR < 150 ml to exclude voiding dysfunction.
Methods
We retrospectively reviewed the charts of all patients who underwent invasive urodynamics from 1 January 2013 to 31 December 2013. Voiding dysfunction was diagnosed if both the invasive urodynamic and the free flow showed abnormal results. We registered the PVR in patients with voiding dysfunction and divided them into groups with PVR < 150 ml and PVR ≥ 150 ml. Patients were then analyzed for bladder outlet obstruction and detrusor underactivity.
Results
Of the 205 patients undergoing invasive urodynamics in 2013, a total of 20 had voiding dysfunction, 2 with PVR ≥ 150 ml. Eighteen patients had PVR < 150 ml (range 0–50 ml); 9 had bladder outlet obstruction while 7 had detrusor underactivity. Two patients were uncategorized. Out of the 20 patients, 7 had no symptoms or complaints indicating voiding dysfunction.
Conclusions
Patients with voiding dysfunction often have normal PVR and so PVR < 150 ml cannot exclude voiding dysfunction. All patients should be evaluated using free flow measurements along with PVR to obtain a reliable, objective measurement of their voiding pattern, before anti-incontinence surgery.
Similar content being viewed by others
References
Schäfer W, Abrams P, Liao L, Mattiasson A, Pesce F, Spangberg A et al (2002) Good urodynamic practices: uroflowmetry, filling cystometry, and pressure-flow studies. Neurourol Urodyn 21(3):261–274
Clement KD, Lapitan MCM, Omar MI, Glazener CM (1996) Urodynamic studies for management of urinary incontinence in children and adults. Cochrane Database Syst Rev 1:CD003195. 10.1002/14651858.CD003195.pub3/abstract
Pradhan A, Jain P, Latthe PM (2012) Effectiveness of midurethral slings in recurrent stress urinary incontinence: a systematic review and meta-analysis. Int Urogynecol J 23(7):831–841
Osman NI, Chapple CR, Abrams P, Dmochowski R, Haab F, Nitti V et al (2014) Detrusor underactivity and the underactive bladder: a new clinical entity? A review of current terminology, definitions, epidemiology, aetiology, and diagnosis. Eur Urol 65(2):389–398
Haylen BT, de Ridder D, Freeman RM, Swift SE, Berghmans B, Lee J et al (2010) An International Urogynecological Association (IUGA)/International Continence Society (ICS) joint report on the terminology for female pelvic floor dysfunction. Neurourol Urodyn 29(1):4–20
Bradley CS, Rovner ES (2004) Urodynamically defined stress urinary incontinence and bladder outlet obstruction coexist in women. J Urol 171(2 Pt 1):757–760, discussion 760–761
Robinson D, Staskin D, Laterza RM, Koelbl H (2012) Defining female voiding dysfunction: ICI-RS 2011. Neurourol Urodyn 31(3):313–316
Gravina GL, Costa AM, Galatioto GP, Ronchi P, Tubaro A, Vicentini C (2007) Urodynamic obstruction in women with stress urinary incontinence—do nonintubated uroflowmetry and symptoms aid diagnosis? J Urol 178(3 Pt 1):959–963, discussion 963–964
Rachaneni S, Latthe P (2015) Does preoperative urodynamics improve outcomes for women undergoing surgery for stress urinary incontinence? A systematic review and meta-analysis. BJOG 122(1):8–16
Nager CW, Brubaker L, Litman HJ, Zyczynski HM, Varner RE, Amundsen C et al (2012) A randomized trial of urodynamic testing before stress-incontinence surgery. N Engl J Med 366(21):1987–1997
Van Leijsen SAL, Kluivers KB, Mol BWJ, Broekhuis SR, Milani AL, Bongers MY et al (2012) Can preoperative urodynamic investigation be omitted in women with stress urinary incontinence? A non-inferiority randomized controlled trial. Neurourol Urodyn 31(7):1118–1123
Saaby M-L, Lose G (2012) Repeatability of post-void residual urine ≥ 100 ml in urogynaecologic patients. Int Urogynecol J 23(2):207–209
Blaivas JG, Groutz A (2000) Bladder outlet obstruction nomogram for women with lower urinary tract symptomatology. Neurourol Urodyn 19(5):553–564
Tan TL, Bergmann MA, Griffiths D, Resnick NM (2004) Stop test or pressure-flow study? Measuring detrusor contractility in older females. Neurourol Urodyn 23(3):184–189
Abrams P, Cardozo L, Fall M, Griffiths D, Rosier P, Ulmsten U et al (2003) The standardisation of terminology in lower urinary tract function: report from the standardisation sub-committee of the International Continence Society. Urology 61(1):37–49
Sander P, Sørensen F, Lose G (2007) Does the tension-free vaginal tape procedure (TVT) affect the voiding function over time? Pressure-flow studies 1 year and 3½ years after TVT. Neurourol Urodyn 26(7):995–997
Taylor JA, Kuchel GA (2006) Detrusor underactivity: clinical features and pathogenesis of an underdiagnosed geriatric condition. J Am Geriatr Soc 54(12):1920–1932
Sirls LT, Richter HE, Litman HJ, Kenton K, Lemack GE, Lukacz ES et al (2013) The effect of urodynamic testing on clinical diagnosis, treatment plan and outcomes in women undergoing stress urinary incontinence surgery. J Urol 189(1):204–209
Agur W, Housami F, Drake M, Abrams P (2009) Could the national institute for health and clinical excellence guidelines on urodynamics in urinary incontinence put some women at risk of a bad outcome from stress incontinence surgery? BJU Int 103(5):635–639
Patel AK, Chapple CR (2008) Urodynamics in the management of female stress incontinence—which test and when? Curr Opin Urol 18(4):359–364
Van Leijsen SAL, Kluivers KB, Mol BWJ, Hout J in’t, Milani AL, Roovers J-PWR et al (2013) Value of urodynamics before stress urinary incontinence surgery: a randomized controlled trial. Obstet Gynecol 121(5):999–1008
Costantini E, Mearini E, Pajoncini C, Biscotto S, Bini V, Porena M (2003) Uroflowmetry in female voiding disturbances. Neurourol Urodyn 22(6):569–573
Sanses TV, Brubaker L, Xu Y, Kraus SR, Lowder JL, Lemack GE et al (2011) Preoperative hesitating urinary stream is associated with postoperative voiding dysfunction and surgical failure following Burch colposuspension or pubovaginal rectus fascial sling surgery. Int Urogynecol J 22(6):713–719
Conflicts of interest
Niels Klarskov and Gunnar Lose have been cooperating with Laborie in the development and supply of catheters for the use of urethral pressure reflectometry, a urodynamic investigation. Laborie has not given any financial support. Niels Klarskov has received honoraria as a speaker/investigator and travel grants from Astellas. Gunnar Lose has received honoraria as an investigator from Astellas. Yasmine Khayyami has no conflicts of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Khayyami, Y., Klarskov, N. & Lose, G. Post-void residual urine under 150 ml does not exclude voiding dysfunction in women. Int Urogynecol J 27, 467–473 (2016). https://doi.org/10.1007/s00192-015-2854-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00192-015-2854-y